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Table 1 Clinical Characteristics of Patients With SARS-CoV-2 Infection

From: Risk factors and clinical features of deterioration in COVID-19 patients in Zhejiang, China: a single-centre, retrospective study

Characteristic

Total (N = 100)

Non-Severity (n = 51)

Severity (n = 49)

P Value*

Demographics, n (%)

 Age, median (IQR), y

54 (42–64)

50 (36–58)

61 (51–70)

0.0001

 ≥ 50

63 (63)

26 (51)

37 (75.5)

0.0111

 Male sex

63 (63)

25 (49)

38 (77.6)

0.0031

 BMI

24.27 (22.14–25.97)

24.01 (21.53–25.51)

24.44 (23.28–27.01)

0.0339

Mainly underlying conditions, n (%)

 Hypertension

37 (37)

9 (17.6)

28 (57.1)

< 0.0001

 Diabetes mellitus

11 (11)

3 (5.9)

8 (16.3)

0.3574

 Cardiac disease

4 (4)

1 (2)

3 (6)

0.118

Fever on admission-°C

 < 37.5 °C

29 (29)

19 (37.3)

10 (20.4)

0.0635

Fever during hospitalization

 Median highest temperature (IQR)

38.25 (37.5–39)

38.2 (37.6–39)

38.3 (37.5–39)

0.9669

Radiologic findings on admission

    

chest CT — no./total no. (%)

    

 Normal

2 (2)

2 (3.9)

0

0.4952

Initial laboratory findings, median (IQR)

 WBC, 109/L

6.4 (4.1–10.8)

5.15 (3.9–7.6)

9.1 (5.5–13.6)

0.0002

 d-dimer

452.5 (240–857.5)

339 (172–836)

604 (408–953)

0.005

 ALT

22 (15–40.5)

20 (13–41)

24 (15–40)

0.2801

 AST

20.5 (16–34)

20 (16–29)

25 (18–42)

0.0484

 CRP

24.665 (7.785–47.6)

10.9 (3.8–27.9)

39.78 (17.3–58.9)

0.0001

 PCT

0.06 (0.03–0.1)

0.04 (0.03–0.07)

0.07 (0.04–0.15)

0.0039

 IL2

0.95 (0.855–1.82)

0.95 (0.78–1.83)

0.95 (0.95–1.81)

0.5534

 IL6

20.425 (8.78–56.04)

12.52 (6.42–30.46)

38.22 (16.2–81.71)

0.0001

 IL10

4.775 (2.91–8.03)

3.45 (2.16–5.82)

6.93 (4.35–9.63)

< 0.0001

 TNF-a

17.98 (10.945–59.085)

23.29 (12.2–65.49)

12.22 (10.77–36.44)

0.1658

 IFN-r

10.06 (5.12–33.56)

11.4 (4.92–39.71)

9.82 (5.19–28.57)

0.6943

 ALC

703 (402–1119)

1119 (620–1554)

543.5 (367.5–810.5)

0.0002

 Total T cells

348 (233–775)

752 (305–1178)

276.5 (167.5–440)

0.0001

 Th cells

176 (79–431)

376 (176–618)

115 (60.5–214.5)

< 0.0001

 B cells

115 (70–211)

167 (91–213)

93.5 (54.5–163.5)

0.0189

 NK cells

105 (64–183)

154 (70–207)

101 (61.5–155.5)

0.1201

  1. Abbreviation: IQR Inter quartile range, BMI Body mass index, WBC White blood count, ALT Aspartate aminotransferase, AST Alanine aminotransferase, CRP C-reactive protein, PCT Procalcitonin, IL Interleukin, TNF-a Tumor necrosis factor a, IFN Interferon, Th T helper cells, ALC Absolute lymphocyte count, NK cells Natural killer cells
  2. *, Chi-square (χ2) test or Fisher’s exact test was used with P < 0.05 as significant
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BMC Infectious Diseases

ISSN: 1471-2334

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