Table 2 Bacterial and viral findings by pneumococcal nasopharyngeal colonization
No S. pneumoniae colonization n = 45 (37.2%) | S. pneumoniae colonization n = 76 (62.8%) | p-valuea | |
|---|---|---|---|
Bacterial findings | |||
Positive bacterial blood culture (of any cause) | 1/39 (2.6%) | 5/62 (8.1%)b | 0.401 |
Positive S. pneumoniae (blood culture) | 0/39 (0%) | 1/62 (1.6%) | 1.000 |
Positive S. pneumoniae (dry blood spot, RT-PCR) | 0/38 (0%) | 1/64 (1.6%) | 1.000 |
Positive for atypical bacteria in NPW | |||
Bordetella pertussis | 1/40 (2.5%) | 2/70 (2.9%) | 1.000 |
Chlamydophila pneumophila | 0/40 (0%) | 0/70 (0%) | NA |
Legionella pneumophila | 0/40 (0%) | 0/70 (0%) | NA |
Mycoplasma pneumoniae | 0/40 (0%) | 1/70 (1.4%) | 1.000 |
Viral findings | |||
At least one virus identified in NPW | 36/40 (90.0%) | 62/70 (88.6%) | 1.000 |
Multiple (≥2) viruses identified in NPW | 13/36 (36.1%) | 20/62 (32.3%) | 0.697 |
Positive for respiratory syncytial virus | 13/40 (32.5%) | 35/70 (50.0%) | 0.075 |
Positive for rhinovirus | 19/40 (47.5%) | 20/70 (28.6%) | 0.046 |
Positive for influenza virus | 8/40 (20.0%) | 8/70 (11.4%) | 0.220 |
Positive for parainfluenza virus | 5/40 (12.5%) | 13/70 (18.6%) | 0.408 |
Positive for adenovirus | 3/40 (7.5%) | 5/70 (7.1%) | 1.000 |
Positive for bocavirus | 4/40 (10.0%) | 2/70 (2.9%) | 0.188 |
Positive for human metapneumovirus | 2/40 (5.0%) | 2/70 (2.9%) | 0.621 |
Positive for coronavirus | 1/40 (2.5%) | 1/70 (1.4%) | 1.000 |