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Fig. 1 | BMC Infectious Diseases

Fig. 1

From: ODYSSEY clinical trial design: a randomised global study to evaluate the efficacy and safety of dolutegravir-based antiretroviral therapy in HIV-positive children, with nested pharmacokinetic sub-studies to evaluate pragmatic WHO-weight-band based dolutegravir dosing

Fig. 1

Trial Schema. Note: 85 additional children weighing 3 to < 14 kg were randomised to DTG versus SOC and will be followed up for 96 weeks. Abbreviations: ART = Antiretroviral Therapy; NRTI=Nucleos(t) ide reverse transcriptase inhibitors; bPI = boosted-Protease Inhibitors; NNRTI=Non-nucleoside reverse-transcriptase inhibitors; INSTI=Integrase Inhibitors

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