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Table 3 Regimens of antibiotics

From: Antimicrobial therapy and assessing therapeutic response in culture-negative pyogenic vertebral osteomyelitis: a retrospective comparative study with culture-positive pyogenic vertebral osteomyelitis

 

CN group (n = 41)

CP group (n = 32)

p value #

Total (n = 73)

Parenteral antibiotics

41 (100%)

32 (100%)

73 (100%)

 β-Lactam

15 (36.6%)

11 (34.4%)

1.000

26 (35.6%)

  1st generation cephalosporin

10 (24.4%)

3 (9.4%)

0.128

13 (17.8%)

  3rd generation cephalosporin

4 (9.8%)

2 (6.3%)

0.689

6 (8.2%)

  Nafcillin

1 (2.4%)

6 (18.8%)

0.039

7 (9.6%)

 β-Lactam ± others a

6 (14.6%)

5 (15.6%)

1.000

11 (15.1%)

 Glycopeptide ± others b

11 (26.8%)

12 (37.5%)

0.447

23 (31.5%)

 Quinolone

9 (22.0%)

1 (3.1%)

0.036

10 (13.7%)

 Others c

0 (0%)

3 (9.4%)

0.080

3 (4.1%)

Oral antibiotics

33 (77.8%)

12 (38.9%)

0.001

49 (60.5%)

 β-Lactam

7 (17.1%)

1 (3.1%)

0.072

8 (11.0%)

 Quinolone

26 (63.4%)

11 (34.4%)

0.019

37 (50.7%)

  1. CN culture negative, CP culture positive, Data are presented as frequency, a β-lactamase inhibitor, aminoglycoside, b Gentamicin and tazime, c Carbapenem, prepenem, and linezoid, # p value between the CN and CP groups, p values of < 0.05 were considered statistically significant