From: Urine collection in cervical cancer screening – analytical comparison of two HPV DNA assays
hrHPV result | Assay (total) | Urine positive n, % (95%CI) | Vaginal positive n, % (95%CI) | Cervical positive n, % (95%CI) | McNemar test Urine vs. vaginal | McNemar test Urine vs. cervical | |||
---|---|---|---|---|---|---|---|---|---|
Any hrHPV (14 types)a | Cobas (n = 150) | 27 | 18.0 (12.2–25.1) | 44 | 29.3 (22.2–37.3) | 36 | 24.0 (17.4–31.6) | 0.01 | 0.05 |
Clart (n = 150) | 25 | 16.7 (11.1–23.6) | 35 | 23.3 (16.8–30.9) | 31 | 20.7 (14.5–28.0) | 0.04 | 0.31 | |
HPV16/18b,d | Cobas (n = 150) | 6 | 4.0 (1.5–8.5) | 17 | 11.3 (6.7–17.5) | 15 | 10.0 (5.7–15.9) | 0.01 | 0.02 |
Clart (n = 150) | 4 | 2.7 (0.7–6.7) | 9 | 6.0 (2.8–11.1) | 8 | 5.3 (2.3–10.2) | 0.06 | 0.13 | |
hrHPV other (12 types)c,d | Cobas (n = 150) | 24 | 16.0 (10.5–22.9) | 38 | 25.3 (18.6–33.1) | 29 | 19.3 (13.3–26.6) | 0.01 | 0.27 |
Clart (n = 150) | 21 | 14.0 (8.9–20.6) | 31 | 20.7 (14.5–28.0) | 29 | 19.3 (13.3–26.6) | 0.04 | 0.17 |