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Table 3 Prevalence of 23S rRNA gene and parC mutations among M. genitalium positive samples with possible multidrug resistance in Guangzhou, China, 2016–2018

From: Macrolide and fluoroquinolone associated mutations in Mycoplasma genitalium in a retrospective study of male and female patients seeking care at a STI Clinic in Guangzhou, China, 2016-2018

Mutationsa

Count (%)b

A2071G + S83I

8 (5.8)

A2071G + S83R

2 (1.4)

A2071G + S83N

1 (0.7)

A2071G + D87G

1 (0.7)

A2071G + D87N

1 (0.7)

A2071T + S83I

1 (0.7)

A2071T + S83R

2 (1.4)

A2071T + D87N

1 (0.7)

A2071T + D87Y

1 (0.7)

A2072G + G81C

1 (0.7)

A2072G + S83I

40 (29.0)

A2072G + S83R

3 (2.2)

A2072G + S83N

1 (0.7)

A2072G + D87Y

3 (2.2)

A2072G + S83I + D87Y

1 (0.7)

  1. a Nucleotide positions in 23S rRNA and in parC gene are listed in accordance to the M. genitalium G37 genome (GenBank accession no. NC_000908.2). b Only 138 successfully sequenced samples included