Table 3 Logistic regression analysis of variables associated with hospital mortality (panel A) and 1-year mortality (panel B)
From: Prognostic value of pro-adrenomedullin and copeptin in acute infective endocarditis
A | ||||||||
|---|---|---|---|---|---|---|---|---|
Hospital Mortality | Univariate analysis | Logistic regression | ||||||
No | Yes | Odds Ratio | (95% C.I.) | ^p-value | Odds Ratio | (95% C.I.) | p-value | |
Age | ||||||||
> 62.3 years | 83 | 15 | 1.76 | (0.73–4.25) | 0.276 | |||
≤ 62.3 years | 88 | 9 | ||||||
Gender | ||||||||
Male | 122 | 17 | 1.02 | (0.40–2.68) | 1.000 | |||
Female | 49 | 7 | ||||||
Causative Pathogen | ||||||||
Staph. aureus | 28 | 3 | 1.37 | (0.38–4.90) | 0.772 | |||
Other pathogens | 143 | 21 | ||||||
Infection Type | ||||||||
Prosthetic | 82 | 16 | 2.17 | (0.88–5.34) | 0.126 | |||
Native | 89 | 8 | ||||||
Embolic Event* | ||||||||
Yes | 66 | 10 | 1.13 | (0.47–2.70) | 0.825 | |||
No | 105 | 14 | ||||||
Surgery Indication | ||||||||
Yes | 130 | 20 | 1.57 | (0.51–4.87) | 0.606 | |||
No | 41 | 4 | ||||||
Pro-Adrenomedullin | ||||||||
> 1.05 nmol/L | 77 | 20 | 6.10 | (2.00–18.6) | < 0.001 | 3.29 | (1.04–11.5) | 0.042 |
≤ 1.05 nmol/L | 94 | 4 | ||||||
Procalcitonin | ||||||||
> 0.16 μg/L | 77 | 18 | 3.66 | (1.38–9.67) | 0.008 | 2.23 | (0.79–6.25) | 0.127 |
≤ 0.16 μg/L | 94 | 6 | ||||||
Copeptin | ||||||||
> 12.5 pmol/L | 78 | 19 | 4.53 | (1.61–12.6) | 0.002 | 2.24 | (0.71–7.11) | 0.168 |
≤ 12.5 pmol/L | 93 | 5 | ||||||
C-reactive protein | ||||||||
> 6.10 mg/dL | 81 | 15 | 1.83 | (0.76–4.40) | 0.196 | |||
≤ 6.10 mg/dL | 89 | 9 | ||||||
B | ||||||||
1-Year Mortality | Univariate analysis | Logistic regression | ||||||
No | Yes | Odds Ratio | (95% C.I.) | ^p-value | Odds Ratio | (95% C.I.) | p-value | |
Age | ||||||||
> 62.3 years | 58 | 39 | 2.76 | (1.43–5.32) | 0.003 | 1.91 | (0.94–3.84) | 0.071 |
≤ 62.3 years | 74 | 18 | ||||||
Gender | ||||||||
Male | 97 | 38 | 1.38 | (0.70–2.71) | 0.382 | |||
Female | 35 | 19 | ||||||
Causative Pathogen | ||||||||
Staph. aureus | 20 | 9 | 1.05 | (0.45–2.47) | 1.000 | |||
Other pathogens | 112 | 48 | ||||||
Infection Type | ||||||||
Prosthetic | 61 | 35 | 1.85 | (0.98–3.48) | 0.059 | |||
Native | 71 | 22 | ||||||
Embolic event* | ||||||||
Yes | 52 | 21 | 1.11 | (0.58–2.11) | 0.871 | |||
No | 80 | 36 | ||||||
Surgery Indication | ||||||||
Yes | 102 | 44 | 1.01 | (0.48–2.10) | 1.000 | |||
No | 30 | 13 | ||||||
Pro-Adrenomedullin | ||||||||
> 1.05 nmol/L | 54 | 40 | 3.39 | (1.74–6.60) | < 0.001 | 1.93 | (0.90–4.12) | 0.088 |
≤ 1.05 nmol/L | 78 | 17 | ||||||
Procalcitonin: | ||||||||
> 0.16 μg/L | 63 | 29 | 1.13 | (0.60–2.11) | 0.752 | |||
≤ 0.16 μg/L | 69 | 28 | ||||||
Copeptin | ||||||||
> 12.5 pmol/L | 54 | 42 | 4.04 | (2.04–8.01) | < 0.001 | 2.55 | (1.18–5.54) | 0.017 |
≤ 12.5 pmol/L | 78 | 15 | ||||||
C-reactive protein | ||||||||
> 6.10 mg/dL | 67 | 28 | 1.08 | (0.58–2.02) | 0.874 | |||
≤ 6.10 mg/dL | 64 | 29 | ||||||