Predictor | No. of deaths/total (%) | Adjusted HRa (95% CI) | P value | |
---|---|---|---|---|
Preterm birth | 15/48 (31.3) | 2.25 (1.04, 4.86) | 0.04 | |
Malignancies | 5/11 (45.5) | 2.36 (0.74, 7.56) | 0.15 | |
Prior hospitalization within 6 months | 22/66 (33.3) | 2.40 (1.12, 5.14) | 0.02 | |
Carbapenem-resistant isolate | 21/71 (29.6) | 2.13 (0.98, 4.61) | 0.06 | |
Source of bloodstream infection | ||||
 Primary or catheter-related | 4/43 (9.3) | Ref | – | |
 Pneumonia | 13/73 (17.8) | 1.69 (0.51, 5.58) | 0.39 | |
 Intra-abdominal infection | 16/30 (53.3) | 6.75 (2.11, 21.57) | < 0.01 | |
Organ failure | ||||
 Altered mental status | 12/22 (54.5) | 5.19 (2.50, 10.77) | < 0.01 | |
 Respiratory failure | 24/92 (26.1) | 1.40 (0.61, 3.20) | 0.42 | |
 Shock/hypotension | 15/43 (34.9) | 2.41 (1.21, 4.82) | 0.01 | |
 Hepatic failure | 24/77 (31.2) | 2.90 (1.33, 6.35) | < 0.01 | |
 Renal Failure | 11/33 (33.3) | 2.20 (1.02, 4.73) | 0.04 | |
 Coagulation disorder | 23/58 (39.7) | 4.54 (2.12, 9.72) | < 0.01 | |
Laboratory predictorb | ||||
 Procalcitonin (ng/mL) | < 0.1 | 7/43 (16.3) | Ref |  |
0.1–17 | 15/65 (23.1) | 1.17 (0.43, 3.19) | 0.76 | |
> 17 | 11/38 (28.9) | 1.72 (0.60, 4.91) | 0.31 | |
 C-reactive protein (mg/L) | < 8 | 5/47 (10.6) | Ref |  |
8–77 | 9/60 (15) | 1.48 (0.48, 4.53) | 0.49 | |
> 77 | 19/39 (48.7) | 6.46 (2.26, 18.52) | < 0.01 | |
 Albumin (g/L) | > 35 | 6/40 (15.0) | Ref |  |
28–35 | 8/58 (13.8) | 0.91 (0.32, 2.63) | 0.86 | |
< 28 | 19/48 (39.6) | 3.32 (1.31, 8.40) | 0.01 | |
 Lactate (mmol/L) | < 2 | 17/101 (16.8) | Ref |  |
≥ 2 | 16/45 (35.6) | 3.44 (1.46, 8.11) | < 0.01 |