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Table 4 Antimicrobial susceptibility pattern of bacteria isolated from various samples in febrile children attending HUCSH, 2018–2019

From: Aetiology of acute febrile illness among children attending a tertiary hospital in southern Ethiopia

Name of antimicrobial

E. coli

n (%) (N = 38)

Klebsiella spp.

n (%) (N = 20)

Other Gram-negative

n (%) (N = 15)

S. aureus

n (%) (N = 21)

Other Gram-positive (n/N)

All isolates

n (%)¶

Susceptible

Resistant

Susceptible

Resistant

Susceptible

Resistant

Susceptible

Resistant

Susceptible

Resistant

Susceptible

Resistant

Ampicillin

0 (0)

37 (97.4)

1 (5.3)b

18 (90.0)b

4 (28.6)d

10 (71.4)d

–

–

(1/4)

(3/4)

6 (8.0)m

68 (90.7)m

Trimethoprim-sulfamethoxazole

3 (7.9)

35 (92.1)

3 (15.0)

17 (85.0)

4 (26.7)

11 (73.3)

7 (33.3)

14 (66.7)

(0/1)

(1/1)

17 (17.9)p

78 (82.1)p

Tetracycline

6 (15.8)

30 (78.9)

5 (25.0)

14 (70.0)

5 (35.7)d

7 (50.0)d

3 (15.0)k

16 (80.0)k

(0/4)

(4/4)

19 (19.8)q

71 (74.0)q

Amoxicillin and clavulanic acid

8 (21.1)

26 (68.4)

4 (20.0)

10 (50.0)

6 (42.9)d

7 (50.0)d

–

–

–

–

18 (25.0)r

43 (59.7)r

Ceftriaxone

14 (36.8)

20 (52.6)

7 (35.0)

13 (65.0)

7 (53.8)e

4 (30.8)e

–

–

(0/1)

(1/1)

28 (38.9)r

38 (52.8)r

Ceftazidime

15 (39.5)

21 (55.3)

5 (25.0)

13 (65.0)

9 (60.0)

5 (33.3)

–

–

–

–

29 (39.7)t

39 (53.4)t

Gentamicin

23 (60.5)

14 (36.8)

8 (40.0)

12 (60.0)

7 (63.6)f

4 (36.4)f

15 (71.4)

5 (23.8)

(4/5)

(1/5)

57 (60.0)p

36 (37.9)p

Chloramphenicol

23 (60.5)

15 (39.5)

9 (45.0)

11 (55.0)

9 (64.3)d

2 (14.3)d

18 (85.7)

3 (14.3)

(2/2)

0

61 (64.2)p

31 (32.6)p

Ciprofloxacin

26 (68.4)

8 (21.1)

15 (75.0)

1 (5.0)

13 (86.7)

1 (6.7)

16 (76.2)

4 (19.0)

(3/4)

0

73 (74.5)u

14 (14.3)u

Meropenem

33 (86.8)

2 (5.3)

16 (80.0)

1 (5.0)

7 (46.7)

2 (13.3)

–

–

–

–

56 (76.7)t

5 (6.8)t

Nitrofurantoin*

37 (100)a

0 (0)

15 (93.8)c

0 (0)

7 (87.5)g

1 (12.5)g

5 (100)h

0 (0)

(4/4)

0

68 (97.1)w

1 (1.4)w

Norfloxacin*

27 (73.0)a

9 (24.3)a

14 (87.5)c

1 (5.0)c

10 (90.9)f

1 (9.1)f

4 (80.0)h

1 (20.0)h

(3/4)

(1/4)

58 (79.5)t

13 (17.8)t

Penicillin G

–

 

–

 

–

 

3 (15.0)k

17 (85.0)k

(2/5)

(3/5)

5 (20.0)x

20 (80.0)x

Erythromycin

–

 

–

 

–

 

10 (47.6)

11 (52.4)

(1/2)

(1/2)

11 (47.8)y

12 (52.2)y

Cefoxitin

–

 

–

 

–

 

13 (61.9)

7 (33.3)

(1/1)

0

14 (63.6)z

7 (31.8)z

Clindamycin

–

 

–

 

–

 

17 (81.9)

4 (19.0)

(1/2)

(1/2)

18 (78.3)y

5 (21.7)y

  1. *Tested for urine isolates as recommended by the guideline
  2. Number of given isolates tested for the antimicrobials: E.coli: a(N = 37); Klebsiella species: b(N = 19), c(N = 16); Other Gram-negative bacteria: d(N = 14), e(N = 13), f(N = 11), g(N = 8); S. aureus: h(N = 5), k(N = 20)
  3. ¶ Each type of isolate was tested for subsets of antimicrobials as recommended by the guideline; there are few missing cases: m(N = 75), p(N = 95), q(N = 96), r(N = 72) t(N = 73), u(N = 98), w(N = 70), x(N = 25), y(N = 23), z(N = 22)