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Table 3 Performance of the culture method, MCDA assay, and HRM assay in clinical sputum sample analysis

From: Direct detection of Corynebacterium striatum, Corynebacterium propinquum, and Corynebacterium simulans in sputum samples by high-resolution melt curve analysis

Method

TP

TN

FP

FN

Sensitivity (95% CI)

Specificity (95% CI)

Culture

42

24

0

22

65.6% (52.6–76.7)

100% (82.8–100)

MCDA

59

24

0

5

92.2% (82.0–97.1)

100% (82.8–100)

HRM

63

24

0

1

98.4% (90.5–99.9)

100% (82.8–100)

  1. TP true positive, TN true negative, FP false positive, FN false negative, CI confidence interval, MCDA multiple cross-displacement amplification, HRM high-resolution melting