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Table 1 Baseline clinical characteristics of participants according to the infection of Helicobacter pylori and Clonorchis sinensis

From: Association between renal function and co-infection with Clonorchis sinensis and Helicobacter pylori: a cross-sectional study

Parameters

Total

(n = 4122)

HP(−) + CS(−)

(n = 2248)

HP(+) + CS(−)

(n = 275)

HP(−) + CS(+)

(n = 1392)

HP(+) + CS(+)

(n = 207)

p value*

Age, years

43.0 (35–51)

43.0 (35–50)

44.0 (33–53)

44.0 (36–52)

45 (36–53)

0.01

Gender, male

2955 (71.69%)

1573 (69.97%)

214 (77.82%)

1012 (72.70%)

156 (75.36%)

0.015

BMI, kg/m2

23.7 (21.77–25.29)

23.56 (21.60–25.18)

23.78 (21.83–25.29)

23.82 (21.93–26.96)

24.01 (22.04–25.61)

0.007

ALT,U/L

20.0 (15.0–29.0)

20.3 (15.1–29.2)

20.1 (15.0–28.1)

20.0 (15.2–29.0)

14.0 (20.2–24.0)

0.972

AST, U/L

20.0 (17.0–24.0)

20.1 (17.1–24)

20 (18.0–24.2)

20.3 (17.3–24.0)

21.2 (18.0–25.0)

0.858

ALP, U/L

88.35 (81.62–95.58)

88.22 (81.34–94.97)

87.94 (81.31–95.35)

89.35 (82.27–96.49)

87.61 (79.0–95.44)

0.003

γ-GT, U/L

26.0 (19.0–39.0)

25.0 (18.0–38)

27.00 (19–37)

27.00 (19–41)

40.0 (28.0–64.8)

0.002

TG, mmol/L

1.39 (0.95–2.13)

1.36 (0.94–1.36)

1.44 (0.94–2.24)

1.42 (0.97–2.20)

1.49 (1.01–2.14)

0.031

TC, mmol/L

5.27 (4.65–5.97)

5.23 (4.62–5.90)

5.19 (4.59–5.91)

5.36 (4.71–6.06)

5.22 (4.65–6.07)

0.005

FPG, mmol/L

5.05((4.75–5.43)

5.05 (4.74–5.42)

4.98 (4.67–5.81)

5.06 (4.77–5.42)

5.10 (4.85–5.54)

0.028

TBA, μmol/L

3.64 (2.65–4.73)

3.67 (2.73–4.76)

3.46 (2.32–4.58)

3.63 (2.62–4.73)

3.42 (2.0–4.42)

0.041

HDL, mmol/L

1.44 (1.23–1.68)

1.44 (1.23–1.69)

1.40 (1.19–1.69)

1.44 (1.24–166)

1.39 (1.24–1.63)

0.239

UA, μmol/L

390.55 (329.4–460.23)

385.65 (324.75–452.9)

328.6 (391.5–468.5)

335.23 (399.95–466.37)

402.9 (323.1–470.1)

0.006

β2-MB, mg/L

1.39 (1.21–1.61)

1.39 (1.21–1.60)

1.40 (1.23–1.63)

1.39 (1.21–1.60)

1.46 (1.29–1.99)

< 0.001

LDL, mmol/L

3.20 (2.68–3.76)

3.18 (2.67–3.73)

3.15 (2.65–3.67)

3.23 (2.71–3.85)

3.17 (2.64–3.78)

0.093

CRE, μmol/L

80.65 (69.1–90.5)

79.65 (67.6–90.1)

83.9 (69.8–91.5)

81.0 (69.5–90.6)

84.4 (77.2–93.1)

< 0.001

SBP, mmHg

119 (111–127.5)

118.65 (111–127)

118.56 (111–127.8)

119.9 (111.9–127.8)

117.9 (109.0–126.8)

0.212

DBP, mmHg

73.11 (68.0–78.49)

73 (68–78)

73 (68.00–78)

74.00 (69.00–79)

72.9 (66–748.3)

0.074

BUN, mmol/L

4.57 (3.88–5.32)

4.54 (3.85–5.3)

4.63 (3.99–5.5)

4.59 (3.9–5.28)

4.67 (3.93–5.49)

0.132

eGFR, ml/min/1.73 m2

96.61 (85.05–106.24)

97.18 (85.74–107.02)

94.43 (84.77–104.81)

96.66 (84.53–105.0)

92.22 (79.44–103.75)

< 0.001

Diabetes, n

262 (6.36%)

148 (6.58%)

19 (6.91%)

78 (5.60%)

17 (8.21%)

0.413

Hypertension, n

304 (7.38%)

198 (8.81%)

16 (5.82%)

66 (4.74%)

24 (11.59%)

0.0002

  1. Data are presented as medians (interquartile ranges, IQR) and n (%)
  2. Cs Clonorchis sinensis, Hp Helicobacter pylori, BMI Body mass index, ALT Alanine aminotransferase, AST Aspartate aminotransferase, ALP Alkaline phosphatase, γ-GT γ-glutamyltranspeptidase, TG Triglyceride, TG Triglyceride, TC Total cholesterol, FPG Fasting plasma glucose, HDL High-density lipoprotein, LDL Low-density lipoprotein, CRE Creatinine, BUN Blood Urea Nitrogen, UA Uric Acid, β2−MB β-2-microglobulin, eGFR Estimated glomerular filtration rate
  3. *Comparisons were made among four groups. The χ2 test was used for dichotomous variables while the Kruskal–Wallis H test was used for continuous variables