Skip to main content

Table 2 Clinical characteristics of COVID-19 and non-COVID-19 patients

From: Proposal of COVID-19 Clinical Risk Score for the management of suspected COVID-19 cases: a case control study

  COVID-19
(n = 23)
Non-COVID-19
(n = 108)
P value
Characteristics
 Age, years 68 (54–78) 68.5 (49–78) 0.84
 Male 17 (70.8) 82 (75.9) 0.72
Comorbidities
 Hypertension 8 (34.8) 32 (29.6) 0.63
 Diabetes 4 (17.4) 23 (21.3) 0.78
 Malignancy 6 (26.1) 36 (33.3) 0.63
 Chronic lung disease 5 (26.1) 27 (25.0) 1.00
 Chronic heart failure 4 (17.4) 12 (11.1) 0.48
 Coronary artery disease 3 (13.0) 16 (14.8) 1.00
 Chronic renal disease 2 (8.7) 17 (15.7) 0.52
 Cerebrovascular disease 3 (13.0) 14 (13.0) 1.00
 Immunodeficiency 2 (8.7) 20 (18.5) 0.36
History
 Days from onset of symptoms 5 (3.5–7) 3 (2–7) 0.56
 High-risk exposure history 15 (65.2) 9 (8.3) < 0.001
Symptomsa (n = 23) (n = 94)  
 Fever 21 (92.3) 78 (83.0) 0.15
 Cough 11 (47.8) 30 (31.9) 0.22
 Nasal congestion 2 (8.7) 2 (2.1) 0.25
 Sore throat 4 (17.3) 4 (4.3) 0.047
 Dyspnea 5 (21.7) 22 (23.4) 1.00
 Anosmia or ageusia 3 (13.0) 1 (1.1) 0.02
Respiratory failure 9 (39.1) 29 (30.9) 0.46
Laboratory results (measured value)
 White blood cell count, cells/μL 5180 (4150–6180) 7300 (5575–10,425) < 0.001
 Neutrophil count, cells/μL 3518 (2474–4429) 4800 (3586–8106) 0.007
 Lymphocyte count, cells/μL 866 (690–1149) 1145 (723–1655) 0.13
 Eosinophil count, cells/μL 0 (0–11) 83 (20–180) < 0.001
 Platelet count, ×104 /μL 16.1 (13.8–20.5) 19.6 (16.1–26.6) 0.05
 Lactate dehydrogenase, IU/L 270 (226–390) 210 (168–283) 0.02
 C-reactive protein, mg/dL 5.31 (1.5–10.7) 3.72 (0.57–7.38) 0.12
 Procalcitonin, ng/mL 0.065 (0.05–0.08) 0.12 (0.03–0.62) 0.33
Laboratory results (cut off value)
 White blood cell count < 8000 μL 21/23 (91.3) 59/108 (54.6) < 0.001
 Lymphocyte count < 1000 μL 14/22 (63.6) 56/92 (60.2) 0.81
 Eosinophil count < 50/μL 21/22 (95.5) 33/93 (35.5) < 0.001
 Lactate dehydrogenase > 250 IU/L 13/20 (56.5) 37 /108 (34.3) 0.04
 Procalcitonin < 0.5 ng/mL 12/12 (100) 33/48 (68.6) 0.03
 Procalcitonin < 0.5 ng/mL and C-reactive protein ≥0.5 mg/dL 11/11 (100) 21/36 (58.3) 0.009
CT imaging findings
 CT imaging score 3.50 ± 0.86 2.00 ± 1.23 < 0.001
Differential diagnosis
 High likelihood of COVID-19 10 (43.5) 4 (3.7) < 0.001
 High likelihood of alternative diagnosis 1 (4.3) 79 (73.1)
  1. Data are shown as median (interquartile range), mean ± SD, or number (%)
  2. aData analysis was performed on excluded asymptomatic cases