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Table 1 German centres with CD diagnostics for routine patient care during 2000–2018

From: Describing nearly two decades of Chagas disease in Germany and the lessons learned: a retrospective study on screening, detection, diagnosis, and treatment of Trypanosoma cruzi infection from 2000 – 2018

Center City Type of test Test availability (years) Number of retrieved tests Data availability (years)
Institute of Tropical Medicine and International Health, Charité – Universitätsmedizin in Berlin Berlin in-house IFT 2000–2010 204 2002–2018
in-house ELISA 2000–2018 830
Institute of Medical Microbiology, Immunology and Parasitology, University Hospital Bonn Bonn in-house IFT 2000–2010 201 2004–2018
commercial ELISA 2011–2018 190
commercial RDT 2000–2010 116
Bernhard Nocht Institute for Tropical Medicine Hamburg in-house IFT 2000–2018 2641 2000–2018a
in-house ELISA 2000–2018 2654
PCRb 2000–2018 200
Division of Infectious Diseases and Tropical Medicine,
University Hospital, LMU Munich
Munich in-house IFT 2000–2018 1670 2000–2018
in-house ELISA 2000–2018 1668
PCRb 2013–2018 35
Institute of Tropical Medicine, Medical Department, University Hospital Tübingen Tuebingen in-house IFT 2009–2018 319 2009–2018
    Total 10,728  
  1. CD Chagas disease, ELISA Enzyme-linked immuno-sorbent assay, IFT Immunofluorescence test, PCR Polymerase chain reaction, RDT Rapid diagnostic test
  2. aIndividual positive tests 2000–2018 and negative tests 2010–2018 could be retrieved
  3. bHamburg offered a conventional PCR that was followed up by sequencing of the PCR product if positive, whereas Munich performed a conventional PCR that was followed up with an independent commercially available qPCR if positive (for details please see Supplement S2)