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Table 3 Pathogenicity/virulence factors in group B Streptococcus isolates, belonging to the 5 major multilocus sequence typing (MLST) clonal complexes (CCs), cultured in Slovenia from 2001 to 2018. The most prevalent genotype within each CC and its proportion are shown

From: Genomic and phenotypic characterisation of invasive neonatal and colonising group B Streptococcus isolates from Slovenia, 2001–2018

Clonal complex

Number

(%)

Capsule (cps) [22]

Pili [22]

ALP family (alp1, alpha, rib, R28) [22]

C5a peptidase (scpB)

Laminin-binding protein (lmb)

Fibrinogen-binding protein A (fbsA)

Fibrinogen-binding protein B (fbsB)

Serine-rich proteins (srr) [22]

GBS immunogenic adhesin A (bibA)

Hypervirulent GBS adhesin (hvgA allele)

 

Genotype (%)

CC-1

18

(10.5)

V

(83.3)

1, 2A

(83.3)

R28

(83.3)

allele-5

(72.2)

allele-1

(94.4)

allele-5

(44.4)

allele-2

(88.9)

srr-1

(94.4)

allele-2

(94.4)

neg

(94.4)

CC-12

19

(11.1)

Ib

(63.2)

1, 2A

(89.5)

alpha

(100)

allele-2

(42.1)

allele-1

(100)

allele-2

(36.8)

allele-2

(68.4)

srr-1

(89.5)

allele-2

(94.7)

neg

(100)

CC-17

91

(53.2)

III

(97.8)

1, 2B

(84.6)

rib

(100)

allele-1

(96.7)

allele-3

(74.7)

allele-4

(100)

allele-3

(85.7)

srr-2

(100)

allele-1

(100)

pos

(100)

CC-19

14

(8.2)

III

(57.1)

1, 2A

(92.9)

rib

(92.9)

allele-3

(57.1)

allele-1

(57.1)

null

(100)

allele-2

(78.6)

srr-1

(78.6)

allele-3

(57.1)

neg

(100)

CC-23

22

(12.9)

Ia

(81.8)

2A

(86.4)

alp1

(81.8)

allele-4

(90.9)

allele-1

(100)

allele-1

(86.4)

allele-1

(90.9)

srr-1

(100)

allele-4

(100)

neg

(100)

  1. ALP alpha-like proteins, neg negative, pos positive
  2. Pili, ALP, srr and hvgA genotypes were named in accordance with Metcalf et al. [22]. Alleles of scpB, lmb, fbsA and fbsB were arbitrarily assigned consecutive numbers