Table 2 Demographic characteristics of new smear-positive pulmonary tuberculosis patients and household contacts, India (n = 38)
From: Comparing tuberculosis gene signatures in malnourished individuals using the TBSignatureProfiler
|
Malnourished Index Case (n=23) |
Malnourished Household Contact (n=15) | P-value | |
|---|---|---|---|
| RNA-seq Processing Batch | |||
| Batch 1 | 8 | 1 | |
| Batch 2 | 15 | 14 | |
| Demographic Characteristics | |||
| Male, n(%) | 16 (69.6) | 7 (46.7) | 0.1903 |
| Age, median (range) | 47 (15-67) | 13 (10-23) | <0.0001 |
| Any alcohol use, n (%) | 14 (60.9) | 0 | <0.0001 |
| Risky alcohol use, n (%) | 10 (43.5) | 0 | <0.0001 |
| Ever a smoker, n (%) | 15 (56.5) | 0 | <0.0001 |
| BMI, median (range) | 14.8 (11.5-15.9) | 15.1 (13.7-15.8) | 0.2221 |
| Clinical Characteristics | |||
| AFB smear grade, n(%) | |||
| 1+ | 10 (43.5) | -- | |
| 2+ | 5 (21.7) | -- | |
| 3+ | 8 (34.8) | -- | |
| MGIT time to positive, median (range) | 6 (3-14) | -- | |
| Duration of cough before treatment, median (range) | 4 (2-5) | -- | |
| Tuberculin Skin Test Millimeters of Induration, median (range) | -- | 7 (5-15) | |
