From: Comparing tuberculosis gene signatures in malnourished individuals using the TBSignatureProfiler
 | Malnourished Index Case (n=23) | Malnourished Household Contact (n=15) | P-value |
---|---|---|---|
RNA-seq Processing Batch | |||
 Batch 1 | 8 | 1 |  |
 Batch 2 | 15 | 14 |  |
Demographic Characteristics | |||
 Male, n(%) | 16 (69.6) | 7 (46.7) | 0.1903 |
 Age, median (range) | 47 (15-67) | 13 (10-23) | <0.0001 |
 Any alcohol use, n (%) | 14 (60.9) | 0 | <0.0001 |
 Risky alcohol use, n (%) | 10 (43.5) | 0 | <0.0001 |
 Ever a smoker, n (%) | 15 (56.5) | 0 | <0.0001 |
 BMI, median (range) | 14.8 (11.5-15.9) | 15.1 (13.7-15.8) | 0.2221 |
Clinical Characteristics | |||
 AFB smear grade, n(%) |  |  |  |
  1+ | 10 (43.5) | -- |  |
  2+ | 5 (21.7) | -- |  |
  3+ | 8 (34.8) | -- |  |
 MGIT time to positive, median (range) | 6 (3-14) | -- |  |
 Duration of cough before treatment, median (range) | 4 (2-5) | -- |  |
 Tuberculin Skin Test Millimeters of Induration, median (range) | -- | 7 (5-15) |  |