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Table 2 Antimicrobial susceptibility patterns of 83 S. agalactiae strains collected from Ethiopia by serotype (June 2014 to September 2015)

From: Features of Streptococcus agalactiae strains recovered from pregnant women and newborns attending different hospitals in Ethiopia

Antibiotics

MIC Range (μg/ml)

N (%)

Susceptible n (%)

Intermediate n(%)

Resistant/Non-susceptible* n(%)

Serotypes, Total S. agalactiae = 83 (% based on MIC group)

Ia, n = 18

Ib, n = 11

II, n = 30

III, n = 5

IV, n = 1

V, n = 18

Penicillin

≤0.03

4 (4.82)

83 (100)

   

3 (75)

1 (25)

   

0.06

47 (56.6)

6 (12.8)

22 (46.8)

4 (8.5)

 

9 (19.2)

6 (12.8)

0.12

32 (38.6)

12 (37.5)

5 (15.6)

5 (15.6)

 

1 (3.1)

9 (28.1)

Cefotaxime

≤0.12

81 (97.6)

83 (100)

  

17 (20.9)

11 (13.6)

29 (35.8)

5 (6.2)

1 (1.2)

18 (22.2)

0.25

2 (2.4)

1 (50)

 

1 (50)

   

Levofloxacin

≤0.5

8 (9.6)

79 (95.2)

   

1 (12.5)

4 (50)

2 (25)

1 (12.5)

 

1

66 (79.5)

16 (24.2)

10 (15.2)

22 (33.3)

3 (4.5)

 

15 (22.7)

2

5 (6.0)

2 (40)

 

3 (60)

   

> 4

4 (4.8)

4 (4.8)

  

1 (25)

  

3 (75)

Tetracycline

≤1

10 (12)

10 (12)

  

8 (80)

2 (20)

    

> 8

73 (88)

  

73 (88)

10 (13.7)

9 (12.3)

30 (41.1)

5 (6.9)

1 (1.4)

18 (24.6)

Clindamycin

≤0.12

78 (98.8)

78 (94)

  

18 (23.1)

11 (14.1)

30 (38.5)

4 (5.1)

1 (1.3)

14 (17.9)

32

5 (1.2)

 

5 (6)a

   

1 (20)

 

4 (80)d

Erythromycin

≤0.25

78 (90.2)

78 (94)

  

18 (23.1)

11 (14.1)

30 (38.5)

4 (5.1)

1 (1.3)

14 (17.9)

0.5

1 (0.83)

 

1 (1.2)

    

1 (100)c

  

2

3 (4.1)

        

3 (100)

> 32

1 (0.83)

  

4 (4.8)

     

1 (100)

Daptomycin

≤1

80 (96.4)

80 (96.4)

  

18 (22.5)

10 (12.5)

28 (35)

5 (6.2)

1 (1.3)

18 (22.5)

> 1

3 (3.6)

  

3 (3.6)b

 

1 (33.3)

2 (66.7)

   

Vancomycin

≤0.5

53 (63.9)

83 (100)

  

12 (22.6)

6 (11.3)

17 (32.1)

3 (5.7)

1 (1.9)

14 (26.4)

1

30 (36.1)

  

6 (20)

5 (16.7)

13 (43.3)

2 (6.7)

 

4 (13.3)

Linezolid

≤2

83 (100)

83 (100)

  

18 (21.7)

11 (13.3)

30 (36.1)

5 (6)

1 (1.2)

18 (21.7)

  1. aFour isolates that were clindamycin susceptible were positive for D-zone test and were considered inducibly resistant
  2. bFor daptomycin CLSI has only susceptible (S) interpretation MICs > 1 considered non-susceptible
  3. cOne serotype III isolates that were clindamycin susceptible were positive for D-zone test and were considered inducibly resistant
  4. dThree serotype V isolates that were clindamycin susceptible were positive for D-zone test and were considered inducibly resistant