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Table 2 Diagnostic accuracy of DAT for diagnosis of VL based on different cut off values and Leishmania species

From: The diagnostic accuracy of direct agglutination test for serodiagnosis of human visceral leishmaniasis: a systematic review with meta-analysis

Parameter Leishmania species Cut off
L.donovani L.infantum All 1:800 1:1600 1:3200
Sensitivity 96 [92–98] 92 [83–96] 96 [92–98] 95 [66–100] 97 [94–99] 96 [93–97]
Specificity 98 [93–99] 98 [15–100] 95 [86–99] 99 [93–100] 87 [83–90] 93 [73–99]
Positive Liklihood Ratio 48.6 [13.6–174] 40 [0.2–8793] 21 [6.6–66.5] 107 [12.7–901] 7.5 [5.6–10] 14.5 [3.1–66.6]
Negative Liklihood Ratio 0.04 [0.02–0.08] 0.09 [0.04–0.18] 0.04 [0.02–0.08] 0.05 [0.01–0.44] 0.03 [0.01–0.07] 0.05 [0.03–0.08]
Diagnostic Odds Ratio 1228 [280–5393] 467 [1–147,442] 467 [114–1912] 2206 [155–31,482] 236 [83–674] 309 [56–1721]