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Fig. 4 | BMC Infectious Diseases

Fig. 4

From: Kinetic changes in virology, specific antibody response and imaging during the clinical course of COVID-19: a descriptive study

Fig. 4

Kinetic changes in the chest CT imaging findings for patients with COVID-19.Case 3 at the initial stage of COVID-19 (week 1 after onset) shows the inflammation in the middle and lower lobes of the right lung, and the increase in flake density in the middle lobe of the right lung and lower lobe of the left lung at week 2. The inflammation in both lungs was completely absorbed at week 5. Case 4 at the initial stage of the disease (week 1) shows the unremarkable CT imaging, and the local inflammation detected in the lower left lobe of both lungs at week 2, which was absorbed at week 6. Case 5 at the initial stage of the disease (week 1) shows the infection in the left upper lobe and right lower lobe, which remained in these locations with an expanded range at week 2. This decreased to scattered inflammation (presented as a thin shadow) in the upper lobe of the left lung, and was absorbed in the right lung at week 8. Case 6 at the initial stage of the disease (week 1) shows the normal CT imaging, and the pneumonia in the lower lobe of the right lung at week 3. There was no inflammation in both lungs at week 7. Case 7 at the initial stage of the disease (week 1) shows a tiny inflammation in the lower left lung. The pneumonia scattered in both lungs at week 3, and was completed absorbed at week 8. Case 8 at the initial stage of the disease (week 1) shows a tiny inflammation of the upper left lung. This was scattered with flakes, some lesions were actually transformed in both lungs at week 2, and these were absorbed with the formation of local fibrosis at week 7. Case 9 at the initial stage of the disease (week 1) shows the increased and thickened texture in both lungs, the patchy shadows in the lower part of two lungs, and the shadowed glass density. The inflammatory lesions disappeared, but localized fibrosis occurred at week 8.Case 10 at the initial stage of the disease (week 1) shows the tiny flake inflammation in both lungs, and the dense and consolidated scattered flake ground glass in both lungs at week 2. Most of the inflammation absorbed with residual lesion and local fibrosis at week 7.Case 11 at the initial stage of the disease (week 1) shows the dense scattered shadow of flaky ground glass in both lungs, and the dense scattered flake ground glass that expanded in both lungs at week 2. This was almost completely absorbed at week 6. Case 12 (no lung CT at week 1) presents a scattered flocculent density with increased shadow and blurred edges, which could be mainly observed in the left lower lobe at week 3. This was absorbed in both lungs at week 7.Case 13 at the initial stage of the disease (week 1) shows the dense flaky ground glass in the lower lobe of both lungs. The ground glass lesion expanded in the range, but the density decreased in the lower lobe of both lungs at week 2. The inflammation was absorbed in the left lung, and residual inflammation occurred in the right lung at week 5.Case 14 (no week 1 CT) presents a tiny inflammation in the lower part of the right lung at week 2, which was completely absorbed at week 7. Case 16 at the initial stage of the disease (week 1) shows a scattered membrane glass shadow, which was mainly in the outer zone of both lungs, and a new lesion was detected in addition to the original lesions at week 2. There were high-density patchy and striated shadows on both lungs with fibrosis at the convalescent stage. Case 17 at the initial stage of the disease (week 1) shows the ground glass lesion outside the lower lobe of both lungs. The extent of the lesion increased, and this was scattered in the flake density with increased shadow. Some of the lesions were consolidated, especially under the pleura in both lungs, at week 2, with scattered flake density and increased shadow. Some of the consolidated lesions become narrower with the fibrosis in both lungs at the convalescent stage

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