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Table 4 Distribution of Spa types according to antibiotic non-susceptibility phenotypes for MRSA isolates (n = 1467)

From: Diversity of SCCmec elements and spa types in South African Staphylococcus aureus mecA-positive blood culture isolates

Spa type

Antibiotic non-susceptibility phenotype

Azithromycin

Erythromycin

Clindamycin

Oxacillin

Cefoxitin

Penicillin

Trimethoprim/ Sulfamethoxazole

Daptomycin

Linezolid

Tetracycline

Rifampin

Ciprofloxacin

Levofloxacin

Moxyfloxacin

Gentamicin

t012 (n = 84)

28 (1.90%)

81 (5.52%)

71 (4.83%)

84 (5.72%)

84 (5.72%)

84 (5.72%)

11 (0.74%)

0

4 (0.27%)

14 (0.95%)

7 (0.47%)

84 (5.72%)

84 (5.72%)

83 (5.65%)

17 (1.15%)

t018 (n = 9)

4 (0.27%)

8 (0.54%)

7 (0.47%)

8 (0.54%)

9 (0.61%)

9 (0.61%)

0

0

0

1 (0.06%)

1 (0.06%)

9 (0.61%)

9 (0.61%)

9 (0.61%)

2 (0.13%)

t032 (n = 24)

4 (0.27%)

12 (0.81%)

3 (0.20)

24 (1.63%)

24 (1.63%)

24 (1.63%)

1 (0.06%)

0

0

2 (0.13%)

43 (2.93%)

23 (1.56%)

23 (1.56%)

23 (1.56%)

3 (0.20)

t037 (n = 697)

327 (22.29%)

690 (47.03%)

81 (5.52%)

693 (47.23%)

695 (47.37%)

698 (47.58%)

659 (44.92%)

5 (0.34%)

1 (0.06%)

679 (46.28%)

0

691 (47.10)

688 (46.89%)

690 (47.03%)

681 (46.42%)

t045 (n = 131)

53 (3.6%)

130 (8.86%)

13 (0.88%)

130 (8.86%)

130 (8.86%)

130 (8.86%)

11 (0.74%)

2 (0.13%)

4 (0.27%)

18 (1.22%)

6 (0.40%)

25 (1.70%)

24 (1.63%)

26 (1.77%)

123 (8.38%)

t064 (n = 49)

21 (1.43%)

29 (1.97%)

0

49 (3.34%)

49 (3.34%)

49 (3.34%)

44 (2.99%)

0

0

47 (3.20%)

47 (3.20%)

30 (2.04%)

25 (1.70_

26 (1.77%)

47 (3.20%)

t1257 (n = 269)

79 (5.3%)

164 (11.17)

14 (0.95%)

268 (18.26%)

268 (18.26%)

268 (18.26%)

249 (16.97%)

0

2 (0.13%)

263 (17.92)

255 (17.38%)

264 (17.99%)

231 (15.74%)

231 (15.74%)

252 (17.17%)

t1443 (n = 14)

1 (0.06%)

1 (0.06%)

0

14 (0.95%)

13 (0.88%)

14 (0.95%)

13 (0.88%)

0

0

13 (0.88%)

14 (0.95%)

13 (0.88%)

13 (0.88%)

13 (0.88%)

13 (0.88%)

t1476 (n = 12)

0

5

0

12 (0.81%)

12 (0.81%)

12 (0.81%)

2 (0.13%)

0

0

9 (0.61%)

0

10 (0.68%)

7 (0.47%)

7 (0.47%)

11 (0.74%)

t1971 (n = 23)

2 (0.13%)

19 (1.29%)

1 (0.06%)

23 (1.56%)

23 (1.56%)

23 (1.56%)

23 (1.56%)

0

0

23 (1.56%)

23 (1.56%)

23 (1.56%)

21 (1.42%)

21 (1.42%)

23 (1.56%)

Novel spa types (n = 38)

9 (0.61%)

24 (1.63%)

7 (0.47%)

37 (2.52%)

37 (2.52%)

38 (2.59%)

23 (1.56%)

0

0

25 (1.70%)

16 (1.09%)

31 (2.11%)

29 (1.97%)

27 (1.84%)

27 (1.84%)

Untypeable (n = 5)

3 (0.20%)

4 (0.27%)

1 (0.06%)

5 (0.34%)

5 (0.34%)

5 (0.34%)

3 (0.20%)

0

0

3 (0.20%)

1 (0.06%)

4 (0.27%)

4 (0.27%)

3 (0.20%)

3 (0.20%)

  1. The following spa types were excluded from the table as they accounted for a small number of isolates: t008, t0121, t015, t021, t022, t0379, t059, t10304, t105, t1096, t1107, t11775, t118, t127, t13165, t1467, t148, t1555, t174, t1774, t1813, t186, t1994, t2029, t223, t2293, t230, t238, t2409, t2526, t272, t2724, t294, t304, t324, t355, t379, t421, t4268, t432, t4410, t451, t463, t4833, t4864, t498, t5483, t5691, t578, t6330, t6931, t701, t718, t729, t7962, t840, t8636, t891, t9061, t913, t932, t951
  2. Susceptibility was classified according to CLSI guidelines [26]
  3. Suggested antibiotics approved by the US Food and Drug Administration (FDA) for clinical use were included in the table. Antibiotics excluded were those that are recommended for urine only as well as those that were not tested for using the MicroScan Gram-positive PM-33 panel. In addition, vancomycin was excluded as all isolates were susceptible
  4. A total of 552 isolates were not typed