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Table 1 Subgroup analyses of pooled mortality

From: Is the superbug fungus really so scary? A systematic review and meta-analysis of global epidemiology and mortality of Candida auris

Factors

Group

Number of studies

Pooled crude mortality (95%CI)

I2 (%)

p value

Bloodstream infection

Yes

15

0.45 (0.39–0.51)

41

0.002

No

5

0.21 (0.08–0.33)

40

Ref

Clade

Clade I

11

0.39 (0.31–0.47)

49

0.343

Non- Clade I

4

0.31 (0.14–0.48)

83

Ref

FLC resistance

Higher

10

0.29 (0.21–0.38)

60

0.415

Lower

3

0.49 (0.29–0.70)

70

Ref

AmB resistance

Higher

6

0.29 (0.19–0.40)

45

0.159

Lower

6

0.43 (0.32–0.53)

62

Ref

Continent

Asia

9

0.44 (0.38–0.51)

0

0.000

America

5

0.43 (0.27–0.59)

78

0.164

Africa

2

0.37 (0.21–0.53)

81

0.303

Europe

3

0.20 (0.04–037)

66

Ref

Publication Year

2018–2019

11

0.42 (0.31–0.53)

86

0.769

2016–2017

5

0.39 (0.30–0.48)

0

0.415

2013–2015

3

0.47 (0.31–0.63)

0

Ref

  1. FLC fluconazole, AmB amphotericin B