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Table 2 The sensitivity, specificity, NPV and PPV of FEC, KK, STS and APC techniques for the diagnosis of STHs against the gold standard among school children in ANRS, from October to December, 2019. (n = 520)

From: Evaluating the performance of diagnostic methods for soil transmitted helminths in the Amhara National Regional State, Northwest Ethiopia

 

“Gold” standard

Method

Species

Result

Pos

Neg

Sensitivity

Specificity

NPV

PPV

% (95% CI)

% (95% CI)

% (95% CI)

% (95% CI)

FEC

AL

pos

13

0

32.5 (20.1–48.0)

100 (99.2–100)

94.7 (92.4–96.3)

100 (77.2–100)

Neg

27

480

HW

pos

113

0

64.2 (56.9–70.9)

100 (98.9–100)

84.5 (80.7–87.7)

100 (96.7–100)

Neg

63

344

TT

pos

3

0

75.0 (31.0–95.4)

100 (99.3–100)

99.8 (98.9–100)

100 (43.9–100)

Neg

1

516

STHs

pos

127

0

57.9 (51.0–64.5)

100 (98.8–100)

78.4 (74.0--82.2)

100 (96.8–100)

Neg

85

308

KK

AL

pos

20

0

50.0 (35.2–64.8)

100 (99.2–100)

96.0 (93.9–97.4)

100 (83.9–100)

Neg

20

480

HW

pos

98

0

55.7 (48.3–62.8

100 (98.9–100)

81.5 (77.5–84.9)

100 (96.2–100)

Neg

78

344

TT

pos

3

0

75.0 (31.0–95.4)

100 (99.3–100)

99.8 (98.9–100)

100 (43.9–100)

Neg

1

516

STHs

pos

117

0

55.2 (48.5–61.7)

100 (98.8–100)

76.4 (72.0–80.3)

100 (96.8–100)

Neg

95

308

STS

AL

pos

32

0

80.0 (65.2–89.5)

100 (99.2–100)

98.4 (96.8–99.2)

100 (89.3–100)

Neg

8

480

HW

pos

137

0

77.8 (71.1–83.3)

100 (98.9–100)

89.8 (86.4–92.5)

100 (97.3–100)

Neg

39

344

TT

pos

4

0

100 (51.0–100)

100 (99.3–100)

100 (99.3–100)

100 (51.0–100)

Neg

0

516

STHs

pos

168

0

79.2 (73.3–84.2)

100 (98.8–100)

87.5 (83.6–90.6)

100 (97.8–100)

Neg

44

308

APC

HW

pos

152

0

86.4 (80.5–90.7)

100 (98.9–100)

93.5 (90.5–95.6)

100 (97.5–100)

Neg

24

344

  1. AL A. lumbricoides, HW Hookworm, TT T. trichiura, CI confidence interval, PPV positive predictive value, NPV negative predictive value