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Table 2 The sensitivity, specificity, NPV and PPV of FEC, KK, STS and APC techniques for the diagnosis of STHs against the gold standard among school children in ANRS, from October to December, 2019. (n = 520)

From: Evaluating the performance of diagnostic methods for soil transmitted helminths in the Amhara National Regional State, Northwest Ethiopia

  “Gold” standard
Method Species Result Pos Neg Sensitivity Specificity NPV PPV
% (95% CI) % (95% CI) % (95% CI) % (95% CI)
FEC AL pos 13 0 32.5 (20.1–48.0) 100 (99.2–100) 94.7 (92.4–96.3) 100 (77.2–100)
Neg 27 480
HW pos 113 0 64.2 (56.9–70.9) 100 (98.9–100) 84.5 (80.7–87.7) 100 (96.7–100)
Neg 63 344
TT pos 3 0 75.0 (31.0–95.4) 100 (99.3–100) 99.8 (98.9–100) 100 (43.9–100)
Neg 1 516
STHs pos 127 0 57.9 (51.0–64.5) 100 (98.8–100) 78.4 (74.0--82.2) 100 (96.8–100)
Neg 85 308
KK AL pos 20 0 50.0 (35.2–64.8) 100 (99.2–100) 96.0 (93.9–97.4) 100 (83.9–100)
Neg 20 480
HW pos 98 0 55.7 (48.3–62.8 100 (98.9–100) 81.5 (77.5–84.9) 100 (96.2–100)
Neg 78 344
TT pos 3 0 75.0 (31.0–95.4) 100 (99.3–100) 99.8 (98.9–100) 100 (43.9–100)
Neg 1 516
STHs pos 117 0 55.2 (48.5–61.7) 100 (98.8–100) 76.4 (72.0–80.3) 100 (96.8–100)
Neg 95 308
STS AL pos 32 0 80.0 (65.2–89.5) 100 (99.2–100) 98.4 (96.8–99.2) 100 (89.3–100)
Neg 8 480
HW pos 137 0 77.8 (71.1–83.3) 100 (98.9–100) 89.8 (86.4–92.5) 100 (97.3–100)
Neg 39 344
TT pos 4 0 100 (51.0–100) 100 (99.3–100) 100 (99.3–100) 100 (51.0–100)
Neg 0 516
STHs pos 168 0 79.2 (73.3–84.2) 100 (98.8–100) 87.5 (83.6–90.6) 100 (97.8–100)
Neg 44 308
APC HW pos 152 0 86.4 (80.5–90.7) 100 (98.9–100) 93.5 (90.5–95.6) 100 (97.5–100)
Neg 24 344
  1. AL A. lumbricoides, HW Hookworm, TT T. trichiura, CI confidence interval, PPV positive predictive value, NPV negative predictive value