Fig. 8

MSCs did not significantly affect viral proliferation, mouse morbidity, and mortality. a Infectious virus titers in lungs and brains of MSC- and mock-treated groups. Viral titers were expressed as the mean Log TCID₅₀ per tissue ± standard error of 6 mice. b Comparison of viral RNA synthesis between MSC- and mock-treated groups by RT-PCR. The amounts of viral RNA synthesis were expressed as log (mean copy number per tissue) ± standard error. d pi: days post-inoculation. c The body weights of mice in MSC-treated D2–4-6 subgroup, mock-treated D2–4-6 subgroup, and control group: daily body weights (% of day 0) ± standard error. d The survival rates of mice in MSC-treated D2–4-6 subgroup, mock-treated D2–4-6 subgroup, and control group. The survival rates were analyzed by Kaplan-Meier curves. There was no significant difference between the two subgroups