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Table 7 Comparison of D-PCR and routine diagnostic methods

From: Evaluation of the performance of an in-house duplex PCR assay targeting the IS6110 and rpoB genes for tuberculosis diagnosis in Cameroon

Diagnostic methods Outcome   D-PCR, n (%) Chi-square p-value
n Positive Negative
Direct microscopy Positive 47 45 (95.7) 2 (4.3) 67.3 <  0.001
Negative 82 17 (20.7) 65 (79.3)   
Concentrated microscopy Positive 49 47 (95.9) 2 (4.1) 72.5 <  0.001
Negative 80 15 (18.8) 65 (81.3)   
LJ cultures Positive 51 48 (94.1) 3 (5.9) 69.1 <  0.001
Negative 72 13 (18.1) 59 (81.9)