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Table 7 Comparison of D-PCR and routine diagnostic methods

From: Evaluation of the performance of an in-house duplex PCR assay targeting the IS6110 and rpoB genes for tuberculosis diagnosis in Cameroon

Diagnostic methods

Outcome

 

D-PCR, n (%)

Chi-square

p-value

n

Positive

Negative

Direct microscopy

Positive

47

45 (95.7)

2 (4.3)

67.3

<  0.001

Negative

82

17 (20.7)

65 (79.3)

  

Concentrated microscopy

Positive

49

47 (95.9)

2 (4.1)

72.5

<  0.001

Negative

80

15 (18.8)

65 (81.3)

  

LJ cultures

Positive

51

48 (94.1)

3 (5.9)

69.1

<  0.001

Negative

72

13 (18.1)

59 (81.9)