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Table 1 Description of the studies included in the systematic review and meta- analysis

From: The epidemiology of tuberculosis-associated hyperglycemia in individuals newly screened for type 2 diabetes mellitus: systematic review and meta-analysis

Author

Diagnostic

Sample size

Age

Mean/median baseline blood glucose of newly screened patients for type 2 DM

n: newly detected hyperglycemia at baseline

n: unresolved hyperglycemia and %

Duration of follow up

Independent risk factors

Loss to follow up

Singh et al. (India, 1984) [17]

OGTT

52

Range 19–60 years with a mean age of 30.5 years

NA

23

6 (26%)

3 months

 

No loss to follow up

Kishore et al. (India,1971)

OGTT

90

Mean age of patients: 29.4

NA

19

5 (26%)

3 months

 

No loss to follow up

Olubuyo et al. (Nigeria, 1990) [18]

OGTT

54

Mean age of patients: 34.9 (SD: 14.4)

NA

23

7 (30%)

3 months

 

No loss to follow up

Kornfeld et al. (India, 2016) [19]

OGTT

153

Mean age of patients with newly diagnosed DM: 46.7 (± 10.7)

HbA1c: 6.8 (6.2–9.3)

33

27 (82%)

3 months

 

Loss to follow up (n = 24); unclear which patients

Basoglu et al. (Turkey, 1999) [20]

OGTT

58

Mean age of patients: 41.9 (15–82 years)

NA

11

10 (91%)

3 months

 

Loss to follow up (n = 17); unclear which patients

Boillat et al. (Tanzania, 2016)

AIC

530

Mean age of patients 35.9 (SD: 12)

NA

296

86 (29%)

5 months

 

Loss to follow up (n = 15); unclear which patients

Gupte et al. (India, 2018) [21]

AIC

392

Median age of patients: 31 (IQR: 23–44)

Median 8.5% (IQR: 6.7–11.5)

30

23 (77%)

6 months

 

No loss to follow up

Aftab et al. (Pakistan, 2017) [22]

FPG

462

Mean age of patients with newly diagnosed DM: 43 (95% CI: 41–45)

NA

195

74 (38%)

6 months

 

Unclear if there is loss to follow up

Lin et al. (China, 2017) [23]

FPG

270

Mean age of patients: 42.1 years

NA

13

9 (69%)

6 months

Association between HIV+, smoking and unstable blood glucose levels during TB treatment (aOR: 6.67, 95% CI: 1.24–35.71) and (aOR: 2.66, 95% CI: 1.37–5.2) respectively.

No loss to follow up

Kubjane et al. (South Africa, 2019)

AIC

390

Median age of patients with newly diagnosed DM: 36 (IQR: 30–43)

Median HbA1c: 6.7 (IQR: 6.5–7)

25

6 (24%)

3 months

HIV+ patients have a higher odds of being newly diagnosed with DM at baseline (OR:1.7; 95% CI: 1.0–2.9

Loss to follow up (n = 6)

Philips et al. (South Africa, 2017) [24]

FPG

29

Mean age of patients 33.95 (SD: 12.02)

Mean fasting insulin 28.20 (SD: 33.21)

9

6 (66.7%)

5 months

 

Loss to follow up (n = 30)

  1. AIC Hemoglobin A1C, FPG Fasting Plasma Glucose test, OGTT Oral Glucose Tolerance Test, FBG Fasting Blood Glucose, SD Standard Deviation, IQR Interquartile range