|
Age, years (mean ± SD)
|
44.1 ± 14.0
|
47.9 ± 14.7
|
0.287
|
|
Gender, male (n,%)
|
20 (74.1%)
|
28 (71.8%)
|
0.839
|
|
Predisposing Factors
|
|
Chronic hepatitis B
|
5 (18.5%)
|
4 (10.3%)
|
0.340
|
|
Pulmonary tuberculosis
|
3 (11.1%)
|
2 (5.1%)
|
0.370
|
|
Type 2 diabetes mellitus
|
2 (7.4%)
|
5 (12.8%)
|
0.486
|
|
Autoimmune diseases
|
1 (3.7%)
|
4 (10.3%)
|
0.326
|
|
Solid tumor
|
1 (3.7%)
|
4 (10.3%)
|
0.326
|
|
Symptoms duration, days, (med, range)
|
30 (6–120)
|
30 (8–90)
|
0.331
|
|
Length of hospital stay days, (med, range)
|
77 (12–308)
|
35 (18–73)
|
0.000*
|
|
CSF parameters opening pressure
|
|
≥25 cmH2O(n, %)
|
27 (100%)
|
42 (93.0%)
|
0.107
|
|
CSF WBC count×106/l (med, range)
|
92 (10–649)
|
82 (4–840)
|
0.744
|
|
≥20 (n,%)
|
23 (85.2%)
|
32 (82.1%)
|
0.871
|
|
CSF protein g/l (med, range)
|
0.78 (0.08–2.58)
|
0.71 (0.22–5.10)
|
0.579
|
|
CSF glucose mmol/l (med, range)
|
1.19 (0.00–3.79)
|
0.83 (0.01–3.09)
|
0.273
|
|
CSF cryptococci count/ml (med, range)
|
1398 (0–57,500)
|
9533 (0–263,000)
|
0.002*
|
|
CSF culture positive (+)
|
15 (55.69%)
|
19 (48.7%)
|
0.114
|
|
Brain images (CT or MRI)
|
|
Meningeal enhancement
|
18 (66.7%)
|
18 (46.2%)
|
0.182
|
|
Cryptococcosis-related lesions in brain
|
13 (48.1%)
|
17 (43.6%)
|
0.717
|
|
Hydrocephalus
|
3 (11.1%)
|
3 (7.7%)
|
0.637
|
|
BMRC staging (n, %)
| | |
0.443
|
|
1
|
2 (7.4%)
|
8 (20.5%)
| |
|
2
|
16 (59.3%)
|
10 (25.6%)
| |
|
3
|
9 (33.3%)
|
21 (53.8%)
| |
