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Table 2 Detailed oral manifestations at different timelines of hospitalization

From: Clinical features of gingivostomatitis due to primary infection of herpes simplex virus in children

Characteristics Total
No. (%)
Late Diagnosis
No. (%)
Early Diagnosis
No. (%)
Other Diagnosis No. (%) P-value
Case Number 185 74 65 46  
Symptoms
 Sore throat 91 (49.2) 40 (54.1) 23 (35.4) 28 (60.9) 0.017
 Drooling 23 (12.4) 9 (12.2) 12 (18.5) 2 (4.3) 0.085
Signs
 Ulcers 156 (84.3) 69 (93.2) 61 (93.8) 26 (56.5) < 0.001
  Anterior oral cavity 121 (65.4) 55 (74.3) 56 (86.2) 10 (21.7) < 0.001
  Posterior oral cavity 117 (63.2) 56 (75.7) 36 (55.4) 25 (54.3) 0.016
 Gum swelling/bleeding 125 (67.6) 59 (79.7) 60 (92.3) 6 (13.0) < 0.001
 Exudate coated of tonsils 31 (16.8) 12 (16.2) 4 (6.2) 15 (32.6) 0.001
On admission
 Ulcers
  Anterior oral cavity 82 (44.3) 22 (29.7)a 50 (76.9) 10 (21.7) < 0.001
  Posterior oral cavity 102 (55.1) 45 (60.8) 33 (50.8) 24 (52.2) 0.443
 Gum swelling/bleeding 57 (31.1) 7 (9.5)b 48 (76.2) 2 (4.3) < 0.001
 Exudate coating 30 (16.2) 12 (16.2) 4 (6.2) 14 (30.4) 0.003
During hospitalization
 Ulcers
  Anterior oral cavity 121 (65.4) 55 (74.3)a 56 (86.2)c 10 (21.7) < 0.001
  Posterior oral cavity 117 (63.2) 56 (75.7) 36 (55.4) 25 (54.3) 0.016
 Gum swelling/bleeding 125 (67.6) 59 (79.7)b 60 (92.3)d 6 (13.0) < 0.001
 Exudate coating 31 (16.8) 12 (16.2) 4 (6.2) 15 (32.6) 0.001
  1. aWithin Late Diagnosis group, the percentage of ulcers over anterior oral cavity increased significantly during course of hospitalization (p-value< 0.001)
  2. bWithin Late Diagnosis group, the percentage of gum swelling or bleeding increased significantly during course of hospitalization (p-value< 0.001)
  3. cThe difference of percentage of ulcers over the anterior oral cavity between the Early and Late Diagnosis group became insignificant during the course of hospitalization (p-value = 0.09)
  4. dThe difference of percentage of gum swelling/bleeding between the Early and Late Diagnosis group became insignificant during the course of hospitalization (p-value = 0.051)