Skip to main content

Table 1 Evaluated characteristics of patients with severe COVID-19 infection

From: The use of intravenous immunoglobulin gamma for the treatment of severe coronavirus disease 2019: a randomized placebo-controlled double-blind clinical trial

 

Total

IVIg Group

Control Group

P-value$

Age (years)a

56 (46,62)

55.5 (45,60)

56 (47,66)

0.375

Sex n (%)

Male

41 (69.5)

21 (70)

20 (68.9)

0.931

Female

18 (30.5)

9 (30)

9 (31)

HTN n (%)

13 (22)

7 (23.3)

6 (20.6)

0.807

DM n (%)

16 (27.1)

6 (20)

10 (34.4)

0.211

Chronic lung disease n (%)

2 (3.3)

2 (6.6)

0 (0)

0.157

HR/min

95 (89,105)

92.5 (89,100)

96 (90,108)

0.280

Systolic BP (mmHg)

120 (115,130)

120 (120,130)

120 (110,130)

0.428

Diastolic BP (mmHg)

80 (70,80)

80 (70,80)

80 (70,80)

0.542

RR /min

19 (18,22)

19.5 (18,22)

19 (18,21)

0.927

BT (°C)

37.1 (36.7,37.7)

37.05 (36.5,37.8)

37.1 (36.9,37.6)

0.772

O2 saturation (%)

88 (85,89)

88 (85,89)

88 (85,89)

0.436

WBC (1000/mm3)

5.6 (4.6,8.7)

5.0 (4.2,7)

6.6 (5,10.9)

0.026

Neutrophil (%)

78 (70,83)

74 (70,80)

80 (74,87)

0.114

Lymphocyte (%)

18 (11,22)

19 (14,25)

16 (9,20)

0.085

Hb (g/dl)

13.9 (12.4,15)

13.7 (12.2,15)

14 (13.1,15.1)

0.309

Plt (1000/mm3)

190 (137,226)

186 (133,220)

191 (160,234)

0.457

LDH (U/L)

591 (444,742)

545.5 (473,705)

611 (421,800)

0.677

BUN (mg/dl)

34 (27,58)

30.5 (27,46)

50 (27,68)

0.082

Creatinine (mg/dl)

1.1 (1,1.3)

1 (0.8,1.1)

1.2 (1,1.4)

0.001

K (mEq/L)

4.1 (3.9,4.4)

4 (3.9,4.5)

4.1 (3.9,4.3)

0.813

Na (mEq/L)

138 (136,140)

138 (137,140)

138 (135,143)

0.728

ESR

29 (20,46)

28 (23,50)

31 (20,41)

0.808

AST (U/L)

31 (21,42)

34.5 (21,53)

29 (18,40)

0.271

ALT (U/L)

35 (27,45)

34 (27,42)

38 (24,47)

0.596

BS (mg/dl)

120 (106,174)

118 (105,141)

131 (109,229)

0.295

pH

7.3 (7.3,7.4)

7.4 (7.3,7.4)

7.3 (7.3,7.4)

0.210

PaO2 (mmHg)

45 (38,49)

45 (40,49)

45 (37,50)

0.767

PCO2 (mmHg)

39 (36,45)

38 (35,42)

39 (38,47)

0.084

HCO3 (mEq/L)

24 (21,26)

24 (23,26)

24 (21,26)

0.522

Duration of stay in ICU (days)

3 (2,6)

4 (3,6)

3 (2,4)

0.101

Duration of hospitalization (days)

8 (6,11)

9 (7,13)

7 (6,9)

0.014

  1. IVIg Intravenous immunoglobulin, HR Heart rate, BP Blood pressure, RR Respiratory rate, BT Body temperature, WBC White blood cells, HB Hemoglobin, PLT Platelet, LDH Lactate dehydrogenase, BUN Blood urea nitrogen, K Serum potassium, Na Serum sodium, ESR Erythrocyte sedimentation rate, AST Enzymes aspartate transaminase, ALT alanine aminotransferase, ALP Alkaline phosphatase, FBS Fasting blood sugar, BS Blood sugar, PaO2 Partial pressure of oxygen, PCO2 Partial pressure of carbon dioxide, HCO3 Bicarbonate, ICU Intensive care unit
  2. a Data are presented using median (and IQR), except for the following categories (reported as frequency and percentage): sex, HTN, DM, chronic lung disease. $ Comparison between IVIg and control groups