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Table 3 A comparison of the baseline characteristics between subacute and chronic meningitis and between tuberculous and non-tuberculous meningitis

From: The diagnostic utility of the “Thwaites’ system” and “lancet consensus scoring system” in tuberculous vs. non-tuberculous subacute and chronic meningitis: multicenter analysis of 395 adult patients

Clinical Features Subacute Meningitisa (n = 313) Chronic Meningitisb (n = 82) P value Tuberculous meningitis
(n = 160)
Non-Tuberculous Meningitis
(n = 235)
P- valuec
Median age in years (range) 38 (14–82) 41 (15–76) 0.104 36 (14–82) 40 (18–78) < 0.001
HIV/AIDS d, n (%) 108/313 (34.5) 43/82 (52.4) 0.003 110/160 (68.8) 41/235 (17.4) < 0.001
Presenting Symptoms, n (%)
Duration of symptoms (days), range 10 (2–28) 41 (30–356) < 0.001 15 (6–356) 8 (2–30) < 0.001
Fever 209/313 (66.7) 55/82 (67.1) 0.959 114/160 (71.3) 150/235 (63.8) 0.124
Headache 262/311(84.2) 54/82 (65.9) < 0.001 129/158 (81.6) 187/235 (79.6) 0.612
Nausea/vomiting 180/311 (57.9) 44/82 (53.6) 0.492 48/102 (47.1) 45/89 (50.6) 0.63
Median GCS e (range) 15 (3–15) 15 (3–15) 0.100 11 (3–15) 15 (3–15) < 0.001
CSF Profile
CSF WBC f 150 (3–3405) 120 (2570) 0.526 161 (2–2570) 84 (5_3405) 0.364
CSF protein, mg/dl 108 (21–3500) 131 (21–1900) 0.381 188 (21–3500) 87 (22–466) < 0.001
CSF glucose, mg/dl 46 (14–193) 27 (0–81) < 0.001 27 (0–115) 52 (1–193) < 0.001
Tuberculous meningitis 104/313 (33.2) 56/82 (68.3) < 0.001 N/A N/A N/A
  1. aSubacute meningitis defined as duration of symptoms between 5 and 29 days
  2. bchronic meningitis defined as duration of symptoms > 30 days
  3. cAll statistically significant outcomes signified by bolding the P value
  4. dHuman immunodeficiency virus/Acquired Immunodeficiency Syndrome
  5. eGlasgow Coma scale
  6. fWhite blood cell counts