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Table 1 Baseline characteristics of E. coli bacteremic patients with bUTI versus non-urinary source

From: Presence of urinary symptoms in bacteremic urinary tract infection: a retrospective cohort study of Escherichia coli bacteremia

  Patients with bUTI (N = 284) Patients with non-urinary source (N = 178) p-value
Demographics
 Age categories    0.3666
   < 65 years 85 (29.9%) 41 (23.0%)  
  65–74 years 48 (16.9%) 34 (19.1%)  
  75–84 years 80 (28.2%) 50 (28.1%)  
   > =85 years 71 (25.0%) 53 (29.8%)  
 Age median (IQR) 76.0 (62.0–84.7) 77.9 (66.7–86.0) 0.0408
 Female 207 (72.9%) 86 (48.3%) < 0.0001
 Long term care home 44 (15.5%) 16 (9.0%) 0.0469
Admitting service    0.0018
 Medicine 264 (93.0%) 147 (82.6%)  
 Surgery 18 (6.3%) 27 (15.2%)  
 ICU 2 (0.7%) 4 (2.3%)  
Charlson comorbidity score    0.0875
 0 181 (63.7%) 96 (53.9%)  
 1 39 (13.7%) 27 (15.2%)  
  > =2 64 (22.5%) 55 (30.9%)  
Charlson comorbidity
 Stroke 21 (7.4%) 8 (4.5%) 0.2416
 Dementia 17 (6.0%) 10 (5.6%) > 0.9999
 Diabetes 22 (7.8%) 21 (11.8%) 0.1874
 Diabetes with complications 16 (5.6%) 15 (8.4%) 0.2562
Source of infection
 Urinary 284 (0%) 0 (0%)  
 Abdomen 0 (0%) 109 (61.2%)  
 Biliary 0 (0%) 60 (33.7%)  
 Pneumonia 0 (0%) 9 (5.1%)  
History of urinary risk factors
 Chronic indwelling Foley catheter 12 (4.2%) 4 (2.3%) 0.3059
 Benign prostate hypertrophy 16 (5.6%) 17 (9.6%) 0.1373
 Urinary malignancy 13 (4.6%) 6 (3.4%) 0.6341
 Prior urinary tract infection 65 (22.9%) 15 (8.4%) < 0.0001
 Nephrolithiasis 16 (5.6%) 14 (7.9%) 0.3405
 Cystoscopy 8 (2.8%) 0 (0%) 0.0259
 Prostate biopsy 6 (2.1%) 0 (0%) 0.0875
 Other urologic procedure 37 (13.0%) 13 (7.3%) 0.0645
Urinary symptoms
 Dysuria 63 (22.2%) 13 (7.3%) < 0.0001
 Urinary urgency 19 (6.7%) 5 (2.8%) 0.0845
 Urinary frequency 61 (21.5%) 5 (2.8%) < 0.0001
 Gross hematuria 14 (4.9%) 2 (1.1%) 0.0351
 Flank pain 52 (18.3%) 11 (6.2%) 0.0001
 Suprapubic abdominal pain 43 (15.1%) 8 (4.5%) 0.0004
 Urinary retention 11 (3.9%) 5 (2.8%) 0.6112
Urinary signs
 Suprapubic tenderness 20 (7.0%) 8 (4.5%) 0.3193
 CVA tenderness 28 (9.9%) 6 (3.4%) 0.0098
Any urinary symptoms or signs 161 (56.7%) 41 (23.0%) < 0.0001
Urinalysis
 Proteinuria 203 / 249 (81.5%) 99 / 139 (71.2%) 0.0220
 Hematuria 221 / 249 (88.8%) 101 / 139 (72.7%) 0.0001
 Leukocytes 223 / 249 (89.6%) 73 / 139 (52.5%) < 0.0001
 Nitrite 121 / 249 (48.6%) 40 / 139 (28.8%) 0.0002
 Leukocytes or nitrites 230 / 249 (92.4%) 79 / 139 (56.8%) < 0.0001
Severity of Infection
 Delirium 68 (23.9%) 38 (21.4%) 0.5703
 Fever 209 (73.6%) 127 (71.4%) 0.5937
 Sepsis by SIRS criteria 274 (96.5%) 171 (96.1%) 0.8050
 Sepsis by qSOFA criteria 110 (38.7%) 88 (49.4%) 0.0264
 Hypotensive shock SBP < 90 223 (78.5%) 136 (76.4%) 0.6462
 Transfer to ICU in 72 h 19 (6.7%) 21 (11.8%) 0.0630
Outcome
 Death in hospital 17 (6.0%) 12 (6.7%) 0.8442