Table 3 Univariate and multivariate analysis for thirty-day clinical cure in E. coli bacteremic urinary tract infections
From: Oral beta-lactam step down in bacteremic E. coli urinary tract infections
Variable | Unadjusted Analysis | Multivariate Analysis | ||
|---|---|---|---|---|
OR (95% CI) | p-value | OR (95% CI) | p-value | |
Age (per year) | 0.98 (0.93–1.02) | 0.30 | … | … |
Sex (female) | 2.49 (0.60–10.30) | 0.21 | … | … |
DM | 0.29 (0.07–1.22) | 0.09 | 0.50 (0.08–3.04) | 0.45 |
CKD | 0.18 (0.03–0.97) | 0.046 | 0.28 (0.03–3.06) | 0.30 |
Heart Conditions | 0.18 (0.02–1.49) | 0.11 | 0.38 (0.03–4.43) | 0.44 |
Asthma/COPD | 0.78 (0.09–6.69) | 0.82 | … | … |
Immunocompromised | 0.29 (0.03–2.68) | 0.28 | … | … |
Recurrent UTI risk factors | 0.12 (0.02–0.63) | 0.01 | 0.15 (0.02–0.96) | 0.045 |
CA-UTI | 0.33 (0.04–2.99) | 0.33 | … | … |
Charlson (per unit) | 0.69 (0.52–0.92) | 0.01 | 0.71 (0.41–1.21) | 0.20 |
Pitt (per unit) | 0.72 (0.49–1.04) | 0.08 | 0.66 (0.39–1.10) | 0.11 |
Sepsis | 0.61 (0.14–2.62) | 0.50 | … | … |
Septic Shock | 0.45 (0.05–3.95) | 0.47 | … | … |
ICU admission | 0.49 (0.05–4.28) | 0.52 | … | … |
Beta-lactam allergy | 0.34 (0.06–1.77) | 0.20 | 0.14 (0.02–1.14) | 0.07 |
IV therapy duration | 0.83 (0.67–1.03) | 0.09 | 0.88 (0.65–1.18) | 0.40 |
Total duration | 1.01 (0.80–1.27) | 0.96 | … | … |
Oral beta-lactam step down | 0.34 (0.08–1.47) | 0.15 | 0.31 (0.05–1.90) | 0.21 |