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Table 3 Univariate and multivariate analysis for thirty-day clinical cure in E. coli bacteremic urinary tract infections

From: Oral beta-lactam step down in bacteremic E. coli urinary tract infections

Variable Unadjusted Analysis Multivariate Analysis
OR (95% CI) p-value OR (95% CI) p-value
Age (per year) 0.98 (0.93–1.02) 0.30
Sex (female) 2.49 (0.60–10.30) 0.21
DM 0.29 (0.07–1.22) 0.09 0.50 (0.08–3.04) 0.45
CKD 0.18 (0.03–0.97) 0.046 0.28 (0.03–3.06) 0.30
Heart Conditions 0.18 (0.02–1.49) 0.11 0.38 (0.03–4.43) 0.44
Asthma/COPD 0.78 (0.09–6.69) 0.82
Immunocompromised 0.29 (0.03–2.68) 0.28
Recurrent UTI risk factors 0.12 (0.02–0.63) 0.01 0.15 (0.02–0.96) 0.045
CA-UTI 0.33 (0.04–2.99) 0.33
Charlson (per unit) 0.69 (0.52–0.92) 0.01 0.71 (0.41–1.21) 0.20
Pitt (per unit) 0.72 (0.49–1.04) 0.08 0.66 (0.39–1.10) 0.11
Sepsis 0.61 (0.14–2.62) 0.50
Septic Shock 0.45 (0.05–3.95) 0.47
ICU admission 0.49 (0.05–4.28) 0.52
Beta-lactam allergy 0.34 (0.06–1.77) 0.20 0.14 (0.02–1.14) 0.07
IV therapy duration 0.83 (0.67–1.03) 0.09 0.88 (0.65–1.18) 0.40
Total duration 1.01 (0.80–1.27) 0.96
Oral beta-lactam step down 0.34 (0.08–1.47) 0.15 0.31 (0.05–1.90) 0.21
  1. Abbreviations: CA-UTI catheter-associated urinary tract infection, CKD chronic kidney disease, CI confidence interval, COPD chronic obstructive pulmonary disease, DM diabetes mellitus, ICU intensive care unit, IV intravenous, OR odds ratio, UTI urinary tract infection