Table 4 Testing results, comparing RT-LAMP method on deep nasal swabs to Multiplex tandem RT-PCR performed on both pharyngeal and deep nasal swabs
PCR (repeat) | |||
|---|---|---|---|
Positive | Negative | Total | |
LAMP | |||
Positive | 8 | 0 | 8 |
Negative | 2 | 11 | 13 |
Total | 10 | 11 | 21 |
LAMP single test including low positives | |||
Positive | 8 | 3 | 11 |
Negative | 2 | 8 | 10 |
10 | 11 | 21 | |
(95% CI) | |||
Sensitivity single test | 80% | (44–98%) | |
Specificity single test | 73% | (39–94%) | |
Positive Predictive Value | 73% | (39–94%) | |
Negative Predictive Value | 80% | (44–98%) | |
Sensitivity – 2 LAMP tests | 80% | (44 to 97%) | |
Specificity – 2 LAMP tests | 100% | (72 to 100%) | |
PPV – 2 LAMP tests | 100% | (n/a) | |
NPV – 2 LAMP tests | 85% | (61 to 95%) | |