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Table 4 Testing results, comparing RT-LAMP method on deep nasal swabs to Multiplex tandem RT-PCR performed on both pharyngeal and deep nasal swabs

From: Detecting SARS-CoV-2 at point of care: preliminary data comparing loop-mediated isothermal amplification (LAMP) to polymerase chain reaction (PCR)

  PCR (repeat)  
Positive Negative Total
LAMP
 Positive 8 0 8
 Negative 2 11 13
 Total 10 11 21
LAMP single test including low positives
 Positive 8 3 11
 Negative 2 8 10
  10 11 21
    (95% CI)
Sensitivity single test 80% (44–98%)
Specificity single test 73% (39–94%)
Positive Predictive Value 73% (39–94%)
Negative Predictive Value 80% (44–98%)
Sensitivity – 2 LAMP tests 80% (44 to 97%)
Specificity – 2 LAMP tests 100% (72 to 100%)
PPV – 2 LAMP tests 100% (n/a)
NPV – 2 LAMP tests 85% (61 to 95%)
  1. Positive PCR cases are defined as at least one positive test over 2 days.