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Table 3 Drug-resistant Beijing strains of M.tb with different genetic mutation* (n = 76)

From: Detection of Beijing strains of MDR M. tuberculosis and their association with drug resistance mutations in katG, rpoB, and embB genes

Gene MDR strains, n = 45 RIF resistant strains, n = 47 INH resistant strains, n = 50 EMB resistant strains, n = 44
katG
 315Thr 41 43
 Others/wt 4 7
rpoB
 516Leu or Trp 3 3
 526Arg,Tyr,Asp,Gly or Asn 4 5
 531Leu or Trp 28 29
 526Arg, Tyr.... + 531Leu or trp 6 6
 516Leu or Trp +531Leu or Trp 2 2
 Others/wt 2 2
embB
 306Val 13 13
 306Ile 8 8
 Others/wt 24 23
  1. *Mutation detection was done by Multiplex-allele specific-PCR; MDR #: Resistant to at least INH and RIF with or without resistance to any other anti-tubercular drug. INH isoniazid, RIF rifampicin, STR streptomycin, EMB ethambutol