Table 3 Drug-resistant Beijing strains of M.tb with different genetic mutation* (n = 76)
Gene | MDR strains, n = 45 | RIF resistant strains, n = 47 | INH resistant strains, n = 50 | EMB resistant strains, n = 44 |
|---|---|---|---|---|
katG | ||||
 315Thr | 41 | – | 43 | – |
 Others/wt | 4 | – | 7 | – |
rpoB | ||||
 516Leu or Trp | 3 | 3 | – | – |
 526Arg,Tyr,Asp,Gly or Asn | 4 | 5 | – | – |
 531Leu or Trp | 28 | 29 | – | – |
 526Arg, Tyr.... + 531Leu or trp | 6 | 6 | – | – |
 516Leu or Trp +531Leu or Trp | 2 | 2 | – | – |
 Others/wt | 2 | 2 | – | – |
embB | ||||
 306Val | 13 | – | – | 13 |
 306Ile | 8 | – | – | 8 |
 Others/wt | 24 | – | – | 23 |