Table 4 Hospitalization characteristics and outcomes of CABM patients
Characteristic | N. meningitidis meningitis (n = 55) | S. pneumoniae meningitis (n = 15) | L. monocytogenes meningitis (n = 5) | Other (n = 5) | Meningitis of unknown origin (n = 79) | Total (n = 159) | P value |
|---|---|---|---|---|---|---|---|
Time to antibiotic therapy, minutes, median (IQR) | 30.0 (15.0–60.0) | 50 (30.0–100.0) | 100.0 (50.0–370.0) | 30.0 (30.0–75.0) | 90.0 (30.0–90.0) | 40.0 (30.0–90.0) | 0.067 |
Duration of antibiotic therapy, days, median (IQR) | 13.0 (10.0–16.0) | 17.0 (12.0–22.0) | 26.0 (21.0–29.0) | 15.0 (11.0–17.0) | 13.0 (11.0–16.0) | 14.0 (11.0–16.0) | 0.004 |
The need of intensive care, n (%) | 47 (85.5) | 11 (73.3) | 3 (60.0) | 1 (20.0) | 44 (55.7) | 106 (66.7) | < 0.001 |
Duration of hospitalization in Intensive care unit – days, median (IQR) | 40, 4 (3–5) | 10, 6.50 (4.50–10.0) | 3, 2 (1.0 -NA) | 1, NA | 51, 3 (2.0–4.0) | 105, 3 (3–5) | 0.017 |
Total duration of hospitalization – days, median (IQR) | 15 (12.0–19.0) | 20 (13.0–25.0) | 28 (21.0–30.5) | 15 (11.0–19.5) | 14 (12.0–18.0) | 15 (12–19) | 0.007 |
Unfavorable outcome – n (%) | 11 (20.0) | 3 (20.0) | 2 (40.0) | 1 (20.0) | 8 (10.0) | 25 (15.7) | 0.162 |
Death – n (%) | 5 (9.1) | 1 (6.7) | 0 (0.0) | 0 (0.0) | 3 (3.8) | 9 (5.7) | 0.452 |