Table 3 Laboratory findings of CABM cases according to the etiological agents
Laboratory finding | N. meningitidis meningitis (n = 55) | S. pneumoniae meningitis (n = 15) | L. monocytogenes meningitis (n = 5) | Other (n = 5) | Meningitis of unknown origin (n = 79) | Total (n = 159) | P value |
|---|---|---|---|---|---|---|---|
CSF white cell count – cells per μl, n, median (IQR) | 53, 1706.67 (143.30–7381.33) | 14, 2805,0 (396.90–5333.33) | 5, 225.0 (102.50–592.0) | 4, 3968.16 (1021.33–5290.75) | 76, 1655.66 (78.50–5013.33) | 152, 1706.34 (160.83–5120.0) | 0.227 |
CSF protein – g/l, n, median (IQR) | 49, 4.10 (1.47–6.54) | 13, 3.91 (2.58–6.14) | 5, 2.29 (0.94–5.06) | 4, 6.55 (3.48–89.50) | 64, 1.95 (0.80–4.53) | 135, 2.76 (1.23–5.44) | 0.013 |
CSF glucose – mmol/l, n, median (IQR) | 48, 0.55 (0.30–2.79) | 12, 0.55 (0.30–3.70) | 5, 1.22 (0.67–2.40) | 3, 1.80 (0.30-NA) | 63 2.50 (1.40–3.50) | 131, 2.1 (0.30–3.20) | 0.007 |
WBC – x10e9/l, median (IQR) | 18.30 (14.20–25.70) | 19.52 (14.06–25.48) | 8.40 (6.89–8.49) | 16.32 (14.06–23.54) | 14.0 (9.10–20.99) | 16.1 (9.70–23.8) | < 0.001 |
PLT – x10e9/l, median (IQR) | 172.0 (129–227.0) | 204.0 (161.0–267.0) | 288.0 (198.0–298.50) | 175.0 (119.0–238.0) | 223.0 (153.0–277.0) | 203.0 (142.0–266.0) | 0.048 |
CRP – mg/l, n, median (IQR) | 55, 175.32 (125.24–217.0) | 15, 138.49 (85.0–186.07) | 5, 65.29 (21.07–73.70) | 5, 137.39 (31.96–220.87) | 78, 127.71 (55.73–184.0) | 158, 147.50 (78.43–197.21) | < 0.001 |
Blood glucose – mmol/l, n, median (IQR) | 54, 7.49 (6.65–9.87) | 14, 8.44 (7.37–11.23) | 5, 6.50 (5.55–7.78) | 4, 6.78 (6.33–7.41) | 72, 6.80 (5.95–8.47) | 149, 7.40 (6.33–8.95) | 0.023 |