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Table 2 Laboratory findings of five cases with orbital mucormycosis

From: Orbital mucormycosis in immunocompetent children; review of risk factors, diagnosis, and treatment approach

  Case 1 Case 2 Case 3 Case 4 Case 5
WBC (X103) 9.7 12.2 33.1 10.8 17.3
Hb (mg/dl) 12.7 10.2 11.3 9.9 10.9
Plt (X103) 392 476 640 500 383
BUN/Cr (mg/dl) 6/0.4 5/0.4 12/0.5 6/0.4 15/0.5
Na (mg/dl) 136 141 141 138 142
K (mg/dl) 4.5 5 4.6 4.6 5.3
ESR 41 21 31 22 64
CRP 18 7 > 150 4 1
Serum immunoglobulin levels1 Nla Nla Nla Nla Nla
Dihydrorhodamine (DHR) test 93 130 167 117 90
Peripheral blood flow cytometry2
 CD3 68% 56% 86% 72% 59%
 CD4 37% 33% 55% 39% 37%
 CD8 30% 21% 28% 25% 14%
 CD16 10% 5% 5% 4% 13%
 CD19 22% 42% 15% 23% 28%
 CD20 22% 39% 15% 23% 28%
 CD56 10% 5% 5% 4% 13%
Interferon Gamma receptor Normal Normal Normal Normal Normal
KOH Non-septate broad hyphae Non-septate broad hyphae Non-septate broad hyphae Non-septate broad hyphae Non-septate broad hyphae
Culture3 Negative Positive Positive Negative Negative
Mucormycosis PCR4 Positive Negative Negative Positive Positive
Microscopic examination by (H&E) staining Positive Positive Positive Positive Positive
  1. WBC White blood cell count, Hb Hemoglobin, Plt platelet count, BUN/Cr blood urea nitrogen/creatinine, Na serum sodium, K serum potassium, ESR Erythrocyte sedimentation rate, CRP C-reactive protein, H&E Hematoxylin and Eosin (H&E) staining
  2. 1Including serum IgG, IgM, IgA, and IgE levels
  3. 2Immunophenotyping of the patient’s peripheral blood mononuclear cells (PBMCs) Including CD3, CD4, CD8, CD16, CD19, CD20, and CD56
  4. 3All isolates were cultured on Sabouraud dextrose agar
  5. 4Nested PCR was performed with set of primer for Mucormycosis (as authors described previously reference [12])
  6. aWithin normal limits for age