Skip to main content

Table 3 Laboratory Findings of Patients Infected With COVID-19 on Admission to Hospital

From: Clinical characteristics of 116 hospitalized patients with COVID-19 in Wuhan, China: a single-centered, retrospective, observational study

 

Disease severity

 

Laboratory findings

Normal Range

Total (N = 116)

Non-severe (n = 61)

Severe (n = 55)

PValue

White blood cell count, ×109/L

3.5–9.5

4.9 (3.9–6.1)

5.0 (3.9–5.7)

4.9 (3.8–7.2)

0.3442

 >9.5 × 109/L, No./total No. (%)

 

9/116 (7.8)

1/61 (1.6)

8/55 (14.5)

0.0129

 <3.5 × 109/L, No./total No. (%)

 

17/116 (14.7)

9/61 (14.8)

8/55 (14.5)

1.0000

Neutrophil count, ×109/L

1.8–6.3

3.1 (2.2–4.5)

2.9 (2.1–3.8)

3.4 (2.5–5.8)

0.0134

Lymphocyte count, ×109/L

1.1–3.2

1.0 (0.7–1.3)

1.2 (0.9–1.6)

0.9 (0.6–1.1)

< 0.0001

 <1.1 × 109/L, No./total No. (%)

 

66/116 (56.9)

24/61 (39.3)

42/55 (76.4)

< 0.0001

Total T cell count,  × 106/L

955–2860

590.5 (361.0–941.8)

915.0 (481.0–1246.0)

448 (238.5–644.0)

< 0.0001

 <955 × 106/L, No./total No. (%)

 

65/84 (77.4)

27/43 (62.8)

38/41 (92.7)

0.0014

CD4+ T cell count,  × 106/L

550–1440

335.0 (214.8–493.3)

458.0 (275.0–607.0)

262.0 (156.5–335.0)

0.0002

 <550 × 106/L, No./total No. (%)

 

66/84 (78.6)

29/43 (67.4)

37/41 (90.2)

0.0158

CD8+ T cell count,  × 106/L

320–1250

217.0 (111.3–359.8)

285.0 (144.0–435.0)

157.0 (78.5–297.0)

0.0052

<320 × 106/L, No./total No. (%)

 

46/84 (54.8)

13/43 (30.2)

33/41 (80.5)

< 0.0001

Monocyte count, ×109/L

0.1–0.6

0.4 (0.3–0.6)

0.4 (0.4–0.6)

0.4 (0.2–0.6)

0.4886

Platelet count, ×109/L

125–350

177.0 (137.0–230.0)

179.0 (145.0–236.0)

161.5 (121.8–218.3)

0.1166

Haemoglobinlevel, g/L

130–175

131.0 (118.0–140.0)

129.0 (120.0–140.5)

131.0 (115.0–140.0)

0.7728

Prothrombin time, s

10.0–14.0

12.2 (11.5–13.0)

11.9 (11.5–13.0)

12.4 (11.6–13.1)

0.3330

Activated partial thromboplastin time, s

23.5–39.1

32.3 (30.1–34.8)

32.3 (30.2–34.6)

32.6 (29.8–35.0)

0.8014

D-dimer, ng/mL

0–243

168.0 (92.0–393.5)

122.0 (75.0–254.0)

222.0 (132.5–529.0)

0.0004

 >243 ng/mL, No./total No. (%)

  

15/61 (24.6)

25/55 (45.5)

0.0204

Creatinine, umol/L

45–110

69.5 (56.0–81.0)

68.5 (54.3–75.8)

72.0(58.8–86.5)

0.0156

 >110umol/L, No./total No. (%)

 

8/116 (6.9)

0/61 (0)

8/55 (14.5)

0.0019

Blood urea nitrogen, mmol/L

2.5–6.3

4.4 (3.4–5.8)

3.9 (3.2–5.0)

4.9 (3.5–7.0)

0.0080

 >6.3 mmol/L, No./total No. (%)

 

22/116 (19.0)

5/61 (8.2)

17/55 (30.9)

0.0021

Alanine aminotransferase, U/L

9–50

24.0 (17.3–37.8)

22.0 (15.5–37.5)

27.0 (20.0–39.0)

0.1227

 >50.0 U/L, No./total No. (%)

 

23/116 (19.8)

11/61 (18.0)

12/55 (21.8)

0.6470

Aspartate aminotransferase, U/L

15–40

34.5 (25.0–52.8)

31.0 (22.5–49.5)

38.0 (26.0–59.0)

0.0810

 >40.0 U/L, No./total No. (%)

 

46/116 (39.7)

21/61 (34.2)

25/55 (45.5)

0.2573

Total bilirubin, umol/L

4.42–20.52

11.0 (8.1–14.1)

11.0 (8.3–13.0)

10.5 (7.8–16.3)

0.9308

Creatinekinase–MB, U/L

0–24

17.0 (15.0–21.0)

17.0 (15.0–22.5)

18.0 (15.8–20.0)

0.6960

 >24.0 U/L, No./total No. (%)

 

19/116 (16.4)

12/61 (19.7)

7/55 (12.7)

0.4518

Lactate dehydrogenase, U/L

109–225

245.5 (194.3–319.8)

225.0 (184.0–303.5)

275.0 (212.0–378.0)

0.0041

 >225.0 U/L, No./total No. (%)

 

69/116 (59.5)

30/61 (49.2)

39/55 (70.9)

0.0230

Hypersensitive troponin T, ng/mL

<0.02

0.008 (0.005–0.013)

0.007 (0.004–0.01)

0.0115 (0.006–0.0175)

0.0015

 >0.02 ng/mL, No./total No. (%)

 

16/116 (13.8)

4/61 (6.6)

12/55 (21.8)

0.0288

Myoglobin, ng/mL

28–72

39.4 (22.3–92.7)

26.1 (21.0–47.8)

54.1 (33.4–120.7)

0.0002

 >72.0 ng/mL, No./total No. (%)

 

34/116 (29.3)

12/61 (19.7)

22/55 (40.0)

0.0096

NT-proBNP, pg/mL

 

71.5 (27.0–363.5)

37.0 (19.0–118.8)

233.0 (53.3–693.0)

< 0.0001

elevated cases, No./total No. (%)

 

8/116 (6.9)

1/61 (1.6)

7/55 (12.8)

0.0260

Procalcitonin, ng/mL

0.00–0.50

0.07 (0.03–0.16)

0.05 (0.03–0.09)

0.09 (0.06–0.23)

< 0.0001

 ≥ 0.5 ng/mL, No./total No. (%)

 

8/116 (6.9)

2/61 (3.3)

6/55 (10.9)

0.1473

IL-6, pg/mL

0–7.0

18.7 (7.7–46.4)

11.8 (3.3–27.5)

33.0 (13.1–69.2)

< 0.0001

C-reactive protein level, mg/L

0–10

15.1 (9.0–50.9)

10.0 (7.0–27.5)

40.0 (10.0–8.0)

0.0023

Sodium, mmol/L

137.0–147.0

138.8 (137.1–141.0)

140.0 (138.2–141.7)

138.0 (134.8–139.3)

0.0001

Potassium, mmol/L

3.5–5.3

4.0 (3.5–4.3)

3.9 (3.5–4.3)

4.1 (3.6–4.3)

0.4548

 >5.3 mmol/L, No./total No. (%)

 

1/116 (0.9)

0/61 (0)

1/55 (1.8)

0.4741

 <3.5 mmol/L, No./total No. (%)

 

24/116 (20.7)

12/61 (19.7)

12/55 (21.8)

0.8213

Chloride, mmol/L

99.0–110.0

103.3 (99.8–105.5)

104.1 (101.3–106.2)

102.2 (99.2–103.8)

0.0011

Calcium, mmol/L

2.02–2.6

2.10 (2.04–2.21)

2.14 (2.09–2.28)

2.07 (2.02–2.13)

< 0.0001

Magnesium, mmol/L

0.6–1.2

0.73 (0.68–0.78)

0.76 (0.70–0.79)

0.70 (0.64–0.76)

0.0025