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Table 1 Baseline Characteristics of Patients Infected With COVID-19

From: Clinical characteristics of 116 hospitalized patients with COVID-19 in Wuhan, China: a single-centered, retrospective, observational study

  Disease severity PValue
Total (N = 116) Non-severe (n = 61) Severe (n = 55)  
Age, median (IQR), y 58.5 (47.0–69.0) 56.0 (37.0–64.0) 64.0 (53.0–76.0) <0.001
 0–14 y 0 0 0
 15–49 y 33/116 (28.4) 24/61 (39.3) 9/55 (16.4)
 50–64 y 41/116 (35.3) 23/61 (37.7) 18/55 (32.7)
 ≥ 65 y 42/116 (36.2) 14/61 (23.0) 28/55 (50.9)
Sex –No., %
 Female 36/116 (31.0) 19/61 (31.1) 17/55 (30.9) 1.000
 Male 80/116 (69.0) 42/61 (68.9) 38/55 (69.1)
Comorbidities –No., %
 Any 59/116 (50.9) 24/61 (39.3) 35/55 (63.6) 0.009
 COPD 1/116 (0.9) 0/61 (0.0) 1/55 (1.8) 0.290
 Diabetes 19/116 (16.4) 8/61 (13.1) 11/55 (20.0) 0.317
 Hypertension 45/116 (38.8) 19/61 (31.1) 26/55 (47.3) 0.075
 Coronary heart disease 17/116 (14.7) 4/61 (6.6) 13/55 (23.6) 0.009
 Cerebrovascular disease 8/116 (6.9) 1/61 (1.6) 7/55 (12.7) 0.019
 Malignancy 4/116 (3.4) 0/61 (0.0) 4/55 (7.3) 0.032
 Chronic kidney disease 0/116 (0.0) 0/61 (0.0) 0/55 (0.0)
 Chronic liver disease 2/116 (1.7) 1/61 (1.6) 1/55 (1.8) 0.941
 HIV infection 0/116 (0.0) 0/61 (0.0) 0/55 (0.0)
Signs and symptoms–No., %
 Fever 99/116 (85.3) 49/61 (80.3) 50/55 (91.0) 0.108
 Fatigue 60/116 (51.7) 26/61 (42.6) 34/55 (61.9) 0.039
 Dry cough 61/116 (52.6) 31/61 (50.8) 30/55 (54.5) 0.688
 Anorexia 50/116 (43.1) 27/61 (44.3) 23/55 (41.8) 0.791
 Myalgia 32/116 (27.6) 19/61 (31.1) 13/55 (23.6) 0.366
 Dyspnea 52/116 (44.8) 21/61 (34.4) 31/55 (56.4) 0.018
 Expectoration 31/116 (26.7) 17/61 (27.9) 14/55 (25.5) 0.769
 Hemoptysis 1/116 (0.9) 0/61 (0.0) 1/55 (1.8) 0.290
 Pharyngalgia 15/116 (12.9) 7/61 (11.5) 8/55 (14.5) 0.623
 Nasal obstruction 6/116 (5.2) 4/61 (6.6) 2/55 (3.6) 0.478
 Diarrhea 17/116 (14.7) 14/61 (23.0) 3/55 (5.5) 0.008
 Nausea 10/116 (8.6) 4/61 (6.6) 6/55 (11.0) 0.404
 Dizziness 7/116 (6.0) 2/61 (3.3) 5/55 (9.1) 0.189
 Headache 6/116 (5.2) 5/61 (8.2) 1/55 (1.8) 0.121
 Vomiting 5/116 (4.3) 3/61 (4.9) 2/55 (3.6) 0.734
 Chill 24/116 (20.7) 13/61 (21.3) 11/55 (20.0) 0.901
 Shiver 5/116 (4.3) 3/61 (4.9) 2/55 (3.6) 0.734
 Abdominal pain 3/116 (2.6) 3/61 (4.9) 0/55 (0.0) 0.096
 Chest discomfort 50/116 (43.1) 22/61 (36.1) 28/55 (51.0) 0.107
 Palpitation 13/116 (11.2) 7/61 (11.5) 6/55 (11.0) 0.923
 Sleep disorders 27/116 (23.3) 15/61 (24.6) 12/55 (21.8) 0.724
Onset of symptom to, median (IQR), d
 Hospital admission 8.0 (4.0–11.0) 8.0 (4.0–11.0) 8.0 (4.0–11.0) 0.910
 Dyspnea 4.5 (0.0–9.0) 3.0 (0.0–12.0) 6.0 (1.5–8.5) 0.649
 Heart rate on admission, median (IQR), bpm 86.0 (80.0–98.0) 85.5 (80.0–97.5) 86.0 (80.0–98.0) 0.958
 Respiratory rate on admission, median (IQR) 19.0 (18.0–23.0) 19.0 (18.0–20.0) 20.0 (18.0–25.0) 0.030
 Mean arterial pressure on admission, median (IQR), mmHg 96.7 (86.7–103.3) 96.7 (86.7–103.5) 96.7 (86.7–103.3) 1.000
 Temperature on admission, median (IQR), °C 36.8 (36.5–37.5) 36.7 (36.5–37.3) 37.0 (36.4–37.8) 0.138