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Table 1 Previous cases of C. krusei osteomyelitis

From: Case report: Candida krusei spondylitis in an immunocompromised patient

Reference

Species

Location

Sex/age

Symptoms and signs

Risk factors

Treatment

Results/follow-up

Kaldau et al., 2011 [8]

C. krusei and

C. tropicalis

Feet

M/60 y

Pain, swell, leukocytoclastic vasculitis; BC positive

AB

IV Fluconazole and voriconazole 7 days, switch to AmB for 4 mo, relapse, multiple surgeries eventually amputation.

Resolved after relapse /12 months

Peman et al., 2006 [3]

C. Krusei

Vertebra

M/62 y

Fever, myalgia, painful skin nodules; BC positive

AML, chemotherapy, neutropenia

IV AmB 2 weeks + caspofungin 4 wks followed by itraconazole PO 4 weeks. After relapse caspofungin + voriconazol 6 wks followed by voriconazol PO

Resolved after relapse/6 months

Schilling et al., 2008 [4]

C. Krusei

Vertebra

M/58 y

Lumbar pain, fever; BC positive

AML, chemotherapy, neutropenia, AB

Voriconazole IV 9 days, switch to caspofungin due to ongoing fever for 14 days. Fosofomycin and rifampicin. After 4 mo surgery was performed, caspofungin reinitiated, after 1 mo posaconazole was added for a total of 1 y

Resolved/ 24 months

  1. AB antibiotics, AmB liposomal amphotericin B, AML acute myeloid leukemia, BC blood culture, IV intravenous, M male, mo months, PO per os, y years