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Table 4 Microfilaridemia detection rate by microscopy, actin-qPCR and O-150 LAMP at day 30, 60 and 180 post IVM treatment in Melong HD

From: Differential susceptibility of Onchocerca volvulus microfilaria to ivermectin in two areas of contrasting history of mass drug administration in Cameroon: relevance of microscopy and molecular techniques for the monitoring of skin microfilarial repopulation within six months of direct observed treatment

Time point after treatment (days) Number of consented eligible participants Number of samples collected Proportion positive for microscopy n(%) Proportion positive for real-time PCR n(%) Proportion positive for O-150 LAMP n(%)
D30 44 29 2 (6.9%) 4 (13.8%) 7 (24.1%)
D90 44 44 9 (20.5%) 7 (15.9%) 12 (27.3%)
D180 44 38 9 (23.7%) 9 (23.7%) 16 (42.1%)
Total   111 20 (18.0%) 20 (18.0%) 35 (31.5%)
Difference    P = 0.180 P = 0.520 P = 0. 215
  1. n = number of cases detected by each method