Skip to main content

Table 3 Microfilaridemia detection rates by microscopy, actin-qPCR and O-150 LAMP at day 30, 60 and 180 post IVM treatment in Bafia HD

From: Differential susceptibility of Onchocerca volvulus microfilaria to ivermectin in two areas of contrasting history of mass drug administration in Cameroon: relevance of microscopy and molecular techniques for the monitoring of skin microfilarial repopulation within six months of direct observed treatment

Time point after treatment (days) Number of consented eligible participants Number of samples collected Proportion positive for microscopy n(%) Proportion positive for real-time PCR n(%) Proportion positive for O-150 LAMP n(%)
D30 51 51 11 (21.6%) 12 (23.5%) 15 (29.4%)
D90 51 51 12 (23.5%) 16 (31.4%) 19 (37.3%)
D180 51 48 22 (45.8%) 26 (54.2%) 31 (64.6%)
Total   150 45 (30%) 54 (36.0%) 65 (43.3%)
Significance    P = 0.014 P = 0.005 P = 0.001
  1. n = number of cases detected by each method