Table 4 Laboratory findings of 83 deaths with COVID-19 pneumonia on admission
Variables | Patients, n(%) |
|---|---|
Blood routine | |
 White blood cell count (×109/L; normal range 3.5–9.5) | 9.1(4.7) |
  Decreased | 5(6%) |
  Increased | 34(41%) |
 Neutrophil count (×109/L; normal range 1.8–6.3) | 6.9(4.4–11.5) |
  Increased | 49(59%) |
 Lymphocyte count (×109/L; normal range 1.1–3.2) | 0.6 (0.4–0.9) |
  Decreased | 69(83%) |
 Mononuclear leucocyte(×109/L; normal range 0.1–0.6) | 0.4(0.3–0.5) |
  Increased | 16(19%) |
 Hemoglobin (g/L; normal range 130–175 for men; 115–150 for women) | 116 (104–121) |
  Decreased | 34(41%) |
 Platelets (×109/L; normal range 125–350) | 166(72) |
  Decreased | 24(29%) |
Blood biochemistry | |
 Total bilirubin (μmol/L; normal range 0.0–23.0) | 14.1(9.8–19.9) |
  Increased | 16(19%) |
 Direct bilirubin (μmol/L; normal range 0.0–8.0) | 5.6(4.2–9.3) |
  Increased | 29(35%) |
 Aspartate aminotransferase (U/L; normal range 15.0–40.0) | 43(28–62) |
  Increased | 47(57%) |
 Alanine aminotransferase (U/L; normal range 7.0–40.0) | 25(19–49) |
  Increased | 25(30%) |
 Alkaline phosphatase (U/L; normal range 50–135) | 76(59–105) |
  Increased | 12(14%) |
 Gamma-glutamyl transpeptidas (U/L; normal range 7–45) | 44(23–75) |
  Increased | 41(49%) |
 Albumin (g/L; normal range 40–55) | 33.7(4.1) |
  Decreased | 77(93%) |
 Globulin (g/L; normal range 20–40) | 25.6(22.6–29.0) |
  Decreased | 4(5%) |
  Increased | 2(2%) |
 Lactate dehydrogenase (U/L; normal range120–250) | 493(362–682) |
  Increased | 79(95%) |
 Serum creatinine (μmol/L; normal range 41–81) | 77(55–113) |
  Increased | 39(47%) |
 Blood urea nitrogen (mmol/L; normal range 3.1–8.8) | 9.36(5.50–16.00) |
  Increased | 44(53%) |
Coagulation function | |
 Prothrombin time (s; normal range 9.0–13.0) | 12.9(12.2–14.2) |
  Increased | 36(43%) |
 Activated partial thromboplastin time (s; normal range 25.0–31.3) | 29.1(27.1–32.5) |
  Increased | 27(33%) |
 D-dimer (mg/L; normal range ≤ 0.55) | 4.68(1.09–18.00) |
  Increased | 78(94%) |
Inflammatory biomarkers | |
 Procalcitonin (ng/mL; normal range ≤ 0.10) | 0.23(0.12–0.94) |
  Increased | 69(83%) |
 C-reactive protein (mg/mL; normal range ≤ 10.0) | 85(47–180.0) |
  Increased | 79(95%) |
 Interleukin-6 (pg/mL; normal range ≤ 20.0) a | 57.1(38.2–137.6) |
  Increased | 19/23(82.6%) |
 ESR (mm/h; normal range ≤ 15) b | 39.75(32.10–63.40) |
  Increased | 25/36(69.4%) |
Cardiac biomarkers | |
 Hypersensitive cardiac troponin I (ng/mL; normal range ≤ 0.04) c | 0.27(0.09–1.07) |
  Increased | 30/48(62.5%) |
 NT-pro B-type natriuretic peptide (pg/ml; normal range ≤ 900) d | 872.0(457.2–1914.5) |
  Increased | 19/42(45.2%) |
Blood gas characteristics e | |
 PH (normal range 7.35–7.45) | 7.44(7.39–7.48) |
  PH < 7.35 | 13/57(22.8%) |
  PH > 7.45 | 24/57 (42.1%) |
 PaO2 (mmHg; normal range 80–100) | 58.3(43.4–75.9) |
  PaO2 < 60 mmHg | 44/57 (77.2%) |
 PaCO2 (mmHg; normal range 35–45) | 34.1 (28.5–37.8) |
  PaO2 < 35 mmHg | 33/57 (57.9%) |
  PaO2 > 50 mmHg | 9/57 (15.8%) |
 Standard bicarbonate (mmol/L; normal range 21.0–25.0) | 20.5 (17.8–24.4) |