Induration or erythema diameter not less than 5 mm as results of recombinant fusion protein ESAT6-CFP10 skin test for detecting M. tuberculosis infection

Table 3 The sensitivity and specificity of induration and erythema after EC skin test

	24 h		48 h		72 h
	≥5 mm, N	<5 mm, N	≥5 mm, N	<5 mm, N	≥5 mm, N	<5 mm, N
In TB patients
Induration diameter	536	207	626	117	620	120
Erythema diameter	634	109	675	68	674	66
χ²	38.60		14.82		17.93
P	<0.01		<0.01		<0.01
In bacteriologically positive TB patients
Induration diameter	303	91	341	53	332	62
Erythema diameter	351	43	369	25	368	26
χ²	20.72		11.16		16.58
P	<0.01		<0.01		<0.01
In bacteriologically nagative TB patients
Induration diameter	188	94	227	55	231	48
Erythema diameter	227	55	244	38	244	35
χ²	13.87		3.72		2.39
P	<0.01		0.05		0.12
In extrapulmonary TB patients
Induration diameter	46	21	58	9	57	10
Erythema diameter	56	11	62	5	62	5
χ²	4.11		1.28		1.88
P	0.04		0.26		0.17
In healthy volunteers
Induration diameter	38	1476	134	1380	–	–
Erythema diameter	70	1444	154	1360	–	–
χ²	9.83		1.54
P	<0.01		0.22
In BCG vaccination volunteers
Induration diameter	20	295	16	299	–	–
Erythema diameter	29	286	22	293	–	–
χ²	1.79		1.01
P	0.18		0.32

ISSN: 1471-2334