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Table 1 Comparisons of clinical characteristics of gram-negative bacteraemia between the follow-up blood culture (FUBC) and no-FUBC groups

From: Predictive scoring models for persistent gram-negative bacteremia that reduce the need for follow-up blood cultures: a retrospective observational cohort study

 

FUBC-drawn (n = 1276)

No FUBC-drawn (n = 205)

p-value

Age, years (± SD)

68.85 (± 14.27)

69.2 (± 14.13)

0.744

Sex (M)

628 (49.2%)

117 (57.1%)

0.042*

Body weight (kg)

59.90 (± 11.56)

59.24 (± 12.62)

0.533

Comorbidity

 DM

404 (31.7%)

70 (34.1%)

0.519

 Liver cirrhosis

95 (7.4%)

17 (8.3%)

0.776

 ESRD on HD

2 (1.0%)

35 (2.7%)

0.154

 ESRD on PD

6 (0.5%)

0 (0.0%)

1.000

 Rheumatic disease

18 (1.4%)

1 (0.5%)

0.500

 Haematologic malignancy

136 (10.7%)

7 (3.4%)

0.001*

 Solid malignancy

361 (28.4%)

60 (29.4%)

0.802

 Solid organ transplantation

34 (2.7%)

5 (2.4%)

1.000

 Bone marrow transplantation

28 (2.2%)

1 (0.5%)

0.167

 Intravascular device

308 (24.1%)

19 (9.3%)

0.000*

 Neutropenia

127 (10.0%)

6 (2.9%)

0.002*

 High-dose steroid

24 (1.9%)

1 (0.5%)

0.239

Microorganism

Escherichia coli

722 (56.6%)

113 (55.1%)

0.705

Klebsiella pneumoniae

250 (19.6%)

45 (22.0%)

0.451

Pseudomonas aeruginosa

62 (4.9%)

7 (3.4%)

0.384

 AmpC-encoded Enterobacteriaceaea

100 (7.8%)

21 (10.2%)

0.237

Acinetobacter baumannii

24 (1.9%)

1 (0.5%)

0.239

 ESBL-producing

313 (24.5%)

32 (15.6%)

0.006*

 Other gram-negative

110 (8.6%)

17 (8.3%)

0.895

 PBSI

50 (3.9%)

8 (3.9%)

1.000

Hospital onset

328 (25.7%)

53 (25.9%)

1.000

Site of infection

 Urinary genital tract

502 (39.3%)

71 (34.6%)

0.217

 Liver abscess

56 (4.4%)

7 (3.4%)

0.583

 Biliary

303 (23.7%)

86 (42.0%)

0.000*

 Intra-abdominal

135 (10.6%)

18 (8.8%)

0.462

 Respiratory

56 (4.4%)

5 (2.4%)

0.255

 SSTI

13 (1.0%)

1 (0.5%)

0.707

 Catheter-related

40 (3.1%)

2 (1.0%)

0.109

 Bone and joint infection

12 (0.9%)

1 (0.5%)

1.000

 Cardiovascular

3 (0.2%)

0 (0.0%)

1.000

 CNS infection

3 (0.2%)

0 (0.0%)

1.000

 Primary bacteraemia

143 (11.2%)

10 (4.9%)

0.006*

In-hospital mortality

87 (6.8%)

18 (8.8%)

0.379

  1. SD Standard deviation, M Male, DM Diabetes mellitus, ESRD End-stage renal disease, HD Haemodialysis, PD Peritoneal dialysis, ESBL Extended-spectrum beta-lactamase, PBSI Polymicrobial bloodstream infection, SSTI Skin and soft tissue infection, CNS Central nervous system
  2. aAmpC-encoded Enterobacteriaceae includes Serratia marcescens, Providencia stuartii, Proteus vulgaris, Citrobacter spp., Enterobacter spp., and Morganella morganii
  3. *p < 0.05