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Table 3 Prevalence of most frequently detected TDRM (including NRTI A62 and NNRTI E138) in women, 2010–2018

From: HIV-1 infection among women in Israel, 2010–2018

Drug Class

DRM

HIV-1 Subtype

p value

p value

p value

All

A

C

B

G/AG

Other

A vs. C

B vs. C

A vs. B

N = 337

N = 130

N = 141

N = 34

N = 23

N = 9

   

PI, n (%)

D30N

1 (0.3)

 

1 (0.7)

      

M46I

5 (1.5)

1 (0.8)

4 (2.8)

   

0.222

  

V82MS

1 (0.3)

   

1 (1.5)

    

NRTI, n (%)

M41L

1 (0.3)

 

1 (0.7)

      

A62V

19 (5.6)

17 (13)

2 (1.4)

   

< 0.001

  

D67EGN

5 (1.5)

3 (2.3)

2 (1.4)

   

0.582

  

K70R

3 (0.9)

2 (1.5)

1 (0.7)

   

0.526

  

M184V

5 (1.5)

3 (2.3)

2 (1.4)

   

0.582

  

T215EIS

4 (1.2)

1 (0.8)

3 (2.1)

   

0.376

  

K219Q

1 (0.3)

1 (0.8)

       

NNRTI, n (%)

K101E

1 (0.3)

 

1 (0.7)

      

K103NS

14 (4.2)

5 (3.8)

3 (2.1)

4 (11.8)

2 (8.7)

 

0.407

0.010

0.068

V106M

1 (0.3)

 

1 (0.7)

      

E138AGKQ

19 (5.6)

11 (8.5)

6 (4.3)

1 (3)

1 (4.3)

 

0.156

0.731

0.276

Y181C

5 (1.5)

1 (0.8)

4 (2.8)

   

0.222

  

Y188L

1 (0.3)

1 (0.8)

       

G190AS

6 (1.8)

2 (1.5)

4 (2.8)

   

0.465

  
  1. Data are presented as n (%). Differences in proportions were measured using the chi-squared test. Empty cells, n = zero.
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BMC Infectious Diseases

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