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Table 3 Prevalence of most frequently detected TDRM (including NRTI A62 and NNRTI E138) in women, 2010–2018

From: HIV-1 infection among women in Israel, 2010–2018

Drug Class DRM HIV-1 Subtype p value p value p value
All A C B G/AG Other A vs. C B vs. C A vs. B
N = 337 N = 130 N = 141 N = 34 N = 23 N = 9    
PI, n (%) D30N 1 (0.3)   1 (0.7)       
M46I 5 (1.5) 1 (0.8) 4 (2.8)     0.222   
V82MS 1 (0.3)     1 (1.5)     
NRTI, n (%) M41L 1 (0.3)   1 (0.7)       
A62V 19 (5.6) 17 (13) 2 (1.4)     < 0.001   
D67EGN 5 (1.5) 3 (2.3) 2 (1.4)     0.582   
K70R 3 (0.9) 2 (1.5) 1 (0.7)     0.526   
M184V 5 (1.5) 3 (2.3) 2 (1.4)     0.582   
T215EIS 4 (1.2) 1 (0.8) 3 (2.1)     0.376   
K219Q 1 (0.3) 1 (0.8)        
NNRTI, n (%) K101E 1 (0.3)   1 (0.7)       
K103NS 14 (4.2) 5 (3.8) 3 (2.1) 4 (11.8) 2 (8.7)   0.407 0.010 0.068
V106M 1 (0.3)   1 (0.7)       
E138AGKQ 19 (5.6) 11 (8.5) 6 (4.3) 1 (3) 1 (4.3)   0.156 0.731 0.276
Y181C 5 (1.5) 1 (0.8) 4 (2.8)     0.222   
Y188L 1 (0.3) 1 (0.8)        
G190AS 6 (1.8) 2 (1.5) 4 (2.8)     0.465   
  1. Data are presented as n (%). Differences in proportions were measured using the chi-squared test. Empty cells, n = zero.