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Table 1 Comparison of clinical manifestations between non-survivors and survivors of children with IPD

From: Early clinical predictors for the prognosis of invasive pneumococcal disease

Clinical information

Death, n = 17

Survival, n = 80

P

Age(y)

0.69 (0.49, 1.55)

2.39 (0.90, 3.81)

0.001

Male

11 (64.7%)

45 (56.2%)

0.522

PRISMIII score

21.04 ± 10.09

6.78 ± 12.32

0.000

Symptoms and signs

 Hyperpyrexia

7 (41.2%)

10 (12.5%)

0.010*

 Vomiting

12 (70.6%)

24 (30.0%)

0.002

 Anorexia

16 (94.1%)

48 (60.0%)

0.007

 Lethargy

16 (94.1%)

29 (36.3%)

0.000

 Oliguria

4 (23.5%)

12 (15.0%)

0.295*

Poor perfusion of extremities

13 (76.5%)

10 (12.5%)

0.000*

 Disease category

  

0.000

 Sepsis

0

42

 

 Sepsis with meningitis

17

18

 

 Meningitis alone

0

11

 

 Sepsis with pneumonia

0

9

 

Source of pathogens

  

0.083

 Blood

9

52

 

 Cerebrospinal fluid

8

19

 

 Pleural effusion

0

9

 

Laboratory results

 Hb(g/L)

94.29 ± 25.74

110.42 ±19.23

0.006

 WBC(×  109 /L)

8.45 ± 8.42

19.74 ± 22.67

0.071

 N#(× 109 /L)

6.10 ±6.62

66.67 ± 19.26

0.052

 L#(× 109 /L)

29.48 ± 17.17

24.91 ± 17.34

0.478

 Plt(× 109 /L)

215.07 ± 158.07

352.06 ± 164.66

0.005

 CRP (mg/L)

40.20 ± 66.69

47.42 ± 69.43

0.968

  1. Hyperpyrexia: fever over 40 °C; vomiting: greater than 3 times/d; anorexia: 50% less than of usual; Hb hemoglobin, N# neutrophil absolute value, L# lymphacyte absolute value, CRP C-reactive protein
  2. *Calculated using Fisher’s exact test