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Table 3 Crude and adjusted odds for treatment of early neonatal sepsis according to World Health Organisation guidelines

From: Adherence to World Health Organisation guidelines for treatment of early onset neonatal sepsis in low-income settings; a cohort study in Nepal

  cOR (95% CI) aORa (95% CI) p-value
Background characteristic
 Large volume hospital 5.08 (3.95—6.55) 5.03 (3.85—6.60) < 0.01
 Medium volume hospital 0.21 (0.16—0.26) 0.21 (0.16—0.28) < 0.01
 Small volume hospital 0.61 (0.35—1.05) 0.70 (0.40—1.23) 0.22
 Disadvantaged casteb 1.57 (1.15—2.15) 1.67 (1.21—2.30) < 0.01
 Inborn infant 2.31 (1.73—3.09) 2.24 (1.66—3.03) < 0.01
Clinical presentation
 Lethargy 1.69 (1.16—2.46) 1.60 (1.09—2.36) 0.02
 Tachypnoea (> 60 breaths per minute) 2.12 (1.57—2.89) 1.86 (1.34—2.60) < 0.01
 Grunting 3.99 (2.22—7.16) 3.38 (1.87—6.10) < 0.01
 Fever (> 38 degrees Celsius) 1.45 (1.13—1.87) 1.42 (1.09—1.85) 0.01
 Central cyanosis 3.79 (1.15—12.47) 3.32 (1.00—11.02) 0.05
  1. Abbreviations: cOR crude odds ratios, aOR adjusted odds ratios, CI confidence interval
  2. aAdjusted for time trend and Nepal Perinatal Quality Improvement Project
  3. bDalit and Muslim