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Table 1 General, maternal and infant factors for infants with early onset sepsis during the NePeriQIPa trial, by antibiotic treatment group; Guideline (n = 1172) and Non-Guideline (n = 354)

From: Adherence to World Health Organisation guidelines for treatment of early onset neonatal sepsis in low-income settings; a cohort study in Nepal

Background characteristic Guideline
n (valid %)
Non-guideline
n (valid %)
p-value
General factors
 Size of hospital
  Large (n = 998) 870 (87.2) 128 (12.8) < 0.01
  Medium (n = 467) 261 (55.9) 206 (44.1)
  Small (n = 61) 41 (66.2) 20 (32.8)
 NePeriQIP triala
  Baseline (n = 467) 326 (69.8) 141 (30.2) < 0.01
  Intervention (n = 970) 769 (79.3) 201 (20.7)
 Born at home 62 (6.5) 20 (6.1) 0.81
 Inborn infants 719 (82.3) 211 (66.7) < 0.01
Maternal factors
 Maternal age in years, mean (SD) 24.5 (4.8) 24.8 (0.27) 0.27
 Disadvantaged casteb 276 (23.6) 58 (16.4) < 0.01
 Caesarean section (elective & emergency) 47 (4.3) 21 (6.1) 0.16
Infant factors
 Admission weight, mean (SD) 2820 (612) 2841 (636) 0.58
 Gestational age, mean (SD) 38.5 (2.7) 38.9 (2.9) 0.06
 Apgar 5 min < 7 53 (8.8) 16 (7.7) 0.64
 Outcome (death or referral to higher centre) 96 (8.4) 39 (11.3) 0.10
  1. Missing data: Intervention (n = 89); Born at home (n = 242); Inborn (n = 336); Caesarean section (n = 89); Admission weight (n = 31); Gestational age (n = 616); Apgar 5 min (n = 716); Outcome (n = 39).
  2. aNepal Perinatal Quality Improvement Project
  3. bDalit and Muslim