From: Prediction of treatment failure and compliance in patients with tuberculosis
Treatment success (N = 50) | Treatment failure (N = 52) | P-value | |
---|---|---|---|
Age | 44.0(31.5–65) | 44.5(29.5–67) | 0.84 |
Male sex | 28(56.0%) | 38(73.1%) | 0.11 |
BMI | 21.1 ± 2.88 | 20.9 ± 3.07 | 0.72 |
Smoking | 0.67 | ||
Current | 10(20.0%) | 13(25.0%) | |
Ex- | 10(20.0%) | 7(13.5%) | |
Never | 30(60.0%) | 32(61.5%) | |
Drinking | 0.21 | ||
Heavy | 3(6.0%) | 3(5.8%) | |
Social | 19(38.0%) | 19(36.5%) | |
None | 24(48.0%) | 30(57.7%) | |
Underlying disease | |||
Diabetes | 5(10.0%) | 4(26.9%) | 0.041 |
Lung ds | 3(6.0%) | 4(7.7%) | > 0.99 |
Heart ds | 1(2.0%) | 3(5.8%) | 0.24 |
Liver ds | 2(4.0%) | 1(1.9%) | > 0.99 |
Kidney ds | 1(2.0%) | 3(5.8%) | 0.36 |
Prev TB Hx | 8(16.0%) | 19(36.5%) | 0.01 |
Symptom | |||
Cough/sputum | 20(40.0%) | 29(55.8%) | 0.16 |
Dyspnea | 10(20.0%) | 7(13.5%) | 0.43 |
Chest pain | 7(14.0%) | 3(5.8%) | 0.20 |
Hemoptysis | 1(2.0%) | 3(5.8%) | 0.62 |
Fever | 5(10.0%) | 3(5.8%) | 0.48 |
Weakness | 0(0%) | 1(1.9%) | > 0.99 |
Weight loss | 6(12.0%) | 4(7.7%) | 0.52 |
Asymptomatic | 17(34.0%) | 15(28.8%) | 0.73 |
Enrollment | |||
Newly diagnosed | 42(84.0%) | 29(55.8%) | |
Recurred | 8(16.0%) | 12(23.1%) | |
Retreatment | 0(0%) | 7(13.5%) | |
Default | 0(0%) | 3(5.8%) | |
Social Hx | |||
Occupation | 18(36.0%) | 23(44.2%) | 0.62 |
Marriage | 28(56.0%) | 33(63.5%) | 0.13 |
Medicaid | 6(12.0%) | 1(1.9%) | 0.06 |
CPA | |||
Normal | 4(8.0%) | 2(3.8%) | 0.43 |
Cavity (+) | 8(17.0%) | 26(50.0%) | 0.001 |
Unilateral | 26(52%) | 23(44.2%) | 0.30 |
Bilateral | 17(34%) | 27(51.9%) | |
AFB smear | |||
Positive | 11(23.4%) | 27(51.9%) | |
DST | < 0.001 | ||
All sensitive | 46(92.0%) | 21(40.4%) | |
R to INH | 2(4.0%) | 5(9.6%) | |
R to RFP | 1(2.0%) | 5(9.6%) | |
Any other R | 1(2.0%) | 2(3.8%) | |
Treatment regimen | |||
HREZ | 38(76.0%) | 40(76.9%) | |
HRE | 11(22.0%) | 1(1.9%) | |
Others | 1(2.0%) | 11(21.2%) | |
Drug compliance | |||
Good compliance | 50(100%) | 37(71.2%) | |
Poor compliance | 0(0%) | 15(28.8%) |