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Table 1 Baseline CBC results for subsequent IGRA converters and IGRA-negative participants

From: The potential of CBC-derived ratios (monocyte-to-lymphocyte, neutrophil-to-lymphocyte, and platelet-to-lymphocyte) to predict or diagnose incident TB infection in Tanzanian adolescents

g IGRA-Negative (n = 98) All Converters (n = 47) Early Converters (n = 18) Late Converters (n = 29) Transient Converters (n = 25) Persistent Converters (n = 22)
Laboratory Component Mean (S.D.) Mean (S.D.) p-val Mean (S.D.) p-val Mean (S.D.) p-val Mean (S.D.) p-val Mean (S.D.) p-val
White blood cells (WBCs)
 WBC count (×  103/mcL) 6.14 (1.36) 5.81 (1.36) 0.20 5.79 (1.22) 0.46 5.82 (1.47) 0.24 5.79 (1.43) 0.36 5.83 (1.32) 0.29
 1Neutrophil count (× 103/mcL) 2.66 (0.96) 2.26 (0.93) 0.06 2.34 (0.94) 0.29 2.22 (0.94) 0.08 2.37 (1.00) 0.36 2.15 (0.85) .05
 Neutrophil % 42.5 (8.6) 38.2 (11.8) 0.11 39.6 (11.2) 0.41 37.4 (12.2) 0.12 39.4 (11.1) 0.48 36.8 (12.6) 0.07
 Lymphocyte count (× 103/mcL) 2.68 (0.56) 2.73 (0.74) 0.91 2.66 (0.63) 0.94 2.78 (0.81) 0.92 2.66 (0.61) 0.96 2.82 (0.87) 0.90
 Lymphocyte % 44.5 (7.6) 47.8 (10.0) 0.12 46.5 (9.2) 0.51 48.6 (10.5) 0.11 47.2 (9.6) 0.39 48.5 (10.5) 0.11
 Monocyte count (× 103/mcL) 0.48 (0.151) 0.459 (0.175) 0.40 0.467 (0.153) 0.99 0.454 (0.189) 0.26 0.425 (0.147) 0.10 0.498 (0.197) 0.68
 Monocyte % 7.9 (2.0) 7.9 (2.5) 0.61 8.0 (2.2) 0.92 7.8 (2.7) 0.44 7.3 (1.6) 0.18 8.5 (3.1) 0.52
 Eosinophil count (× 103/mcL) 0.220 (0.259) 0.253 (0.229) 0.26 0.230 (0.222) 0.88 0.268 (0.236) 0.16 0.249 (0.197) 0.17 0.258 (0.266) 0.75
 Eosinophil % 3.5 (3.6) 4.4 (3.9) 0.17 4.2 (4.4) 0.80 4.5 (3.6) 0.09 4.5 (4.0) 0.13 4.3 (3.8) 0.58
 Basophil count (× 103/mcL) 0.100 (0.075) 0.097 (0.068) 0.98 0.093 (0.069) 0.66 0.100 (0.069) 0.77 0.084 (0.036) 0.90 0.112 (0.091) 0.93
 Basophil % 1.6 (1.1) 1.7 (1.2) 0.60 1.7 (1.4) 0.99 1.7 (1.2) 0.46 1.5 (0.8) 0.69 1.9 (1.6) 0.68
Red blood cells (RBCs)
 1,2RBC count (× 106/mcL) 4.8 (0.4) 4.6 (0.5) 0.008 4.7 (0.8) 0.20 4.5 (0.4) 0.008 4.7 (0.6) 0.08 4.5 (0.4) 0.02
 1,2Hemoglobin (g/dL) 12.6 (1.0) 12.3 (1.6) 0.01 12.5 (2.4) 0.08 12.1 (0.9) 0.03 12.4 (2.0) 0.09 12.1 (1.0) 0.02
 1,2,3,4Hematocrit (%) 38.8 (3.0) 37.8 (4.5) 0.005 38.2 (6.5) 0.03 37.5 (2.7) 0.03 38.1 (5.6) 0.04 37.4 (3.0) 0.02
 MCV (fL) 81.9 (6.2) 82.2 (5.7) 0.67 81.4 (6.7) 0.90 82.7 (5.1) 0.50 81.4 (5.2) 0.68 83.1 (6.3) 0.26
 MCH (pg) 26.5 (2.2) 26.8 (2.1) 0.50 26.7 (2.5) 0.58 26.8 (1.9) 0.62 26.6 (2.1) 0.96 27.0 (2.2) 0.30
 MCHC (g/dL) 32.4 (0.9) 32.5 (0.9) 0.36 32.8 (0.8) 0.12 32.4 (1.9) 0.94 32.6 (0.9) 0.31 32.5 (1.0) 0.71
 RDW (%) 16.1 (1.5) 16.7 (2.4) 0.33 16.9 (2.9) 0.38 16.6 (2.2) 0.51 17.2 (3.0) 0.15 16.1 (1.5) 0.99
Platelets
 Platelet count (× 103/mcL) 312 (103) 30 (118) 0.20 306 (141) 0.24 297 (104) 0.38 288 (107) 0.19 315 (131) 0.51
  1. S.D. standard deviation, MCV mean corpuscular volume, MCH mean corpuscular hemoglobin, MCHC mean corpuscular hemoglobin concentration, RDW red cell distribution width