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Table 1 Baseline characteristics and outcomes of validation cohort

From: A surveillance method to identify patients with sepsis from electronic health records in Hong Kong: a single centre retrospective study

  Infection Sepsis P Value
N = 245 N = 245  
Age, years, median (IQR) 69.7 (58.6–83.4) 77.10 (64.0–85.1) 0.007
Age group, No. (%)    0.013
  < 60 68 (27.8) 42 (17.1)  
 60–69 55 (22.4) 48 (19.6)  
 70–79 38 (15.5) 53 (21.6)  
  ≥ 80 84 (34.3) 102 (41.6)  
Male sex, No. (%) 124 (50.6) 145 (59.2) 0.057
Community acquired infection*, No. (%) 223 (91.0) 206 (84.1) 0.02
Positive culture, No. (%) 109 (44.5) 106 (43.3) 0.785
Charlson Comorbidity Index (Non Age Adjusted), median (IQR) 1.0 (0.0–2.00) 1.0 (0.0–3.0) 0.068
Charlson Comorbidity Index group, No. (%)    0.211
 0 116 (47.3) 93 (38.0)  
 1 35 (14.3) 43 (17.6)  
 2 39 (15.9) 47 (19.2)  
  ≥ 3 55 (22.4) 62 (25.3)  
Estimated Baseline SOFA, median (IQR) 0 (0–1) 0 (0–1) 0.113
Estimated Hospital SOFA, median (IQR) 0 (0–1) 4 (2–6) < 0.001
Number of organ dysfunction, No. (%)    < 0.001
 0 129 (52.7) 0 (0.0)  
 1 96 (39.2) 58 (23.7)  
 2 19 (7.8) 105 (42.9)  
 3 1 (0.4) 53 (21.6)  
  ≥ 4 0 (0.0) 29 (11.8)  
Respiratory Dysfunction, No. (%)
 Baseline 0 (0.0) 0 (0.0)
 New/Worsening 3 (1.2) 48 (19.6) < 0.001
 Hospital 3 (1.2) 48 (19.6) < 0.001
Neurological Dysfunction, No. (%)
 Baseline 28 (11.4) 21 (8.6) 0.292
 New/Worsening 10 (4.1) 57 (23.3) < 0.001
 Hospital 38 (15.5) 78 (31.8) < 0.001
Cardiovascular Dysfunction, No. (%)
 Baseline 0 (0.0) 0 (0.0)
 New/Worsening 0 (0.0) 32 (13.1) < 0.001
 Hospital 0 (0.0) 32 (13.1) < 0.001
Liver Dysfunction, No. (%)
 Baseline 0 (0.0) 9 (3.7) 0.01
 New/Worsening, No. (%) 12 (4.9) 103 (42.0) < 0.001
 Hospital 12 (4.9) 105 (42.9) < 0.001
Hematological Dysfunction, No. (%)
 Baseline 8 (3.3) 27 (11.0) 0.001
 New/Worsening 30 (12.2) 131 (53.5) < 0.001
 Hospital 32 (13.1) 139 (56.7) < 0.001
Renal Dysfunction, No. (%)
 Baseline 36 (14.7) 38 (15.5) 0.280
 New/Worsening 27 (11.0) 124 (50.6) < 0.001
 Hospital 52 (21.2) 145 (59.2) < 0.001
Emergency surgery, No. (%) 31 (12.7) 33 (13.5) 0.789
ICU admission, No. (%) 1 (0.4) 33 (13.5) < 0.001
Hospital length of stay, days, median (IQR) 9.0 (5.0–18.0) 13.0 (7.0–23.0) < 0.001
28-day mortality, No. (%) 12 (4.9) 50 (20.4) < 0.001
  1. *Positive bacterial cultures within 48 h of hospital admission
  2. Dysfunction for each system is any estimated SOFA component ≥1. If patient had higher estimated SOFA component in hospital than their baseline score it is considered new/worsening dysfunction
  3. ICU intensive care unit, IQR interquartile range